PTK6 phosphorylates KHDRBS3

Stable Identifier
R-HSA-8849042
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Nuclear PTK6 (BRK) phosphorylates the RNA binding protein KHDRSB3 (SLM2) on an unknown tyrosine residue, thus inhibiting its interaction with RNA. KDRSB3 is a SAM68 (KHDRSB1) family member whose function has been poorly studied (Haegebarth et al. 2004).

Literature References
PubMed ID Title Journal Year
15471878 The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2

Haegebarth, A, Heap, D, Bie, W, Derry, JJ, Richard, S, Tyner, AL

J. Biol. Chem. 2004
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of p-Y342-PTK6 [nucleoplasm]

Orthologous Events
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