PTK6 phosphorylates ARHGAP35

Stable Identifier
R-HSA-8849068
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Activated PTK6 (BRK) phosphorylates ARHGAP35, a Rho GTPase activating protein, on tyrosine residue Y1105 (Shen et al. 2005).

Literature References
PubMed ID Title Journal Year
18829532 Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion

Shen, CH, Chen, HY, Lin, MS, Li, FY, Chang, CC, Kuo, ML, Settleman, J, Chen, RH

Cancer Res. 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of p-Y342-PTK6:ARHGAP35 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed