Reactome | RAB18 [cytosol]

RAB18 [cytosol]

Stable Identifier

R-HSA-8850022

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ras-related protein Rab-18

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NP72 RAB18

Gene Names

RAB18

Chain

chain:1-203, propeptide:204-206

Reference Genes

BioGPS Gene:22931 RAB18

COSMIC (genes):RAB18 RAB18

CTD Gene:22931 RAB18

dbSNP Gene:22931 RAB18

ENSEMBL:ENSG00000099246 RAB18

ENSEMBL_homo_sapiens_GENE:ENSG00000099246.18 RAB18

HGNC:14244 RAB18

KEGG Gene (Homo sapiens):22931 RAB18

Monarch:22931 RAB18

NCBI Gene:22931 RAB18

OMIM:602207 RAB18

UCSC:Q9NP72 RAB18

Reference Transcript

Other Identifiers

11733781_a_at

11733782_x_at

11744479_x_at

11744480_s_at

11747367_a_at

11751040_a_at

11753493_a_at

11753494_x_at

16703495

223336_PM_s_at

223336_s_at

224377_PM_s_at

224377_s_at

224787_PM_s_at

224787_s_at

22931

239637_PM_at

239637_at

2920838

3240101

3240102

3240111

3240119

3240123

3240125

3240127

3240128

3240129

3240130

3240131

3240132

3240133

3240134

3240135

3240136

3240137

3240138

3240139

3240140

3240141

3240147

42713_at

54378_at

65764_at

78719_at

7926836

A_23_P138376

A_24_P132787

A_33_P3299754

GE55827

GE828389

GO:0000166

GO:0001654

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005783

GO:0005789

GO:0005794

GO:0005811

GO:0005829

GO:0005886

GO:0006886

GO:0007264

GO:0007420

GO:0012505

GO:0015031

GO:0016020

GO:0016324

GO:0016787

GO:0019003

GO:0023052

GO:0030667

GO:0031410

GO:0034389

GO:0043226

GO:0048856

GO:0071782

GO:0071786

HMNXSV003046152

Hs.21094.1.A2_3p_a_at

Hs.47995.0.A1_3p_at

ILMN_1691143

ILMN_1906110

PH_hs_0003381

PH_hs_0024980

TC10000192.hg

TC10001958.hg

TC10001959.hg

g12052986_3p_a_at

g12751074_3p_s_at

Participates

as a component of

RAB18:GDP [cytosol] (Homo sapiens)

as a candidate of

RABs [cytosol] (Homo sapiens)

Other forms of this molecule

RAB18 [endoplasmic reticulum membrane]

GGC-RAB18 [endoplasmic reticulum membrane]

GGC-RAB18 [cytosol]

RAB18 [plasma membrane]

RAB18 [secretory granule membrane]

Inferred To

RAB18 [cytosol] (Bos taurus)

RAB18 [cytosol] (Caenorhabditis elegans)

RAB18 [cytosol] (Canis familiaris)

RAB18 [cytosol] (Danio rerio)

RAB18 [cytosol] (Dictyostelium discoideum)

RAB18 [cytosol] (Gallus gallus)

RAB18 [cytosol] (Mus musculus)

RAB18 [cytosol] (Plasmodium falciparum)

RAB18 [cytosol] (Rattus norvegicus)

RAB18 [cytosol] (Sus scrofa)

Rab18 [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_001243340.1, NP_001243339.1, NP_001243344.1, NP_067075.1, NP_001243341.1

OpenTargets

ENSG00000099246

HPA

ENSG00000099246-RAB18

GeneCards

Q9NP72

Ensembl

ENST00000682389, ENST00000356940, ENSG00000099246, ENSP00000507542, ENSP00000507154, ENST00000621805, ENSP00000349415, ENSP00000478479, ENST00000682082

PRO

Q9NP72

Pharos - Targets

Q9NP72

Orphanet

20157

PDB

1X3S

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	9