Reactome | Partially folded GNB2 [cytosol]

Partially folded GNB2 [cytosol]

Stable Identifier

R-HSA-8850536

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Partially folded G-protein subunit beta-2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P62879 GNB2

Gene Names

GNB2

Chain

initiator methionine:1, chain:2-340

Reference Genes

BioGPS Gene:2783 GNB2

COSMIC (genes):GNB2 GNB2

CTD Gene:2783 GNB2

dbSNP Gene:2783 GNB2

ENSEMBL:ENSG00000172354 GNB2

HGNC:4398 GNB2

KEGG Gene (Homo sapiens):2783 GNB2

Monarch:2783 GNB2

NCBI Gene:2783 GNB2

OMIM:139390 GNB2

UCSC:P62879 GNB2

Reference Transcript

RefSeq:NM_005273.3 GNB2

Other Identifiers

0003830193

11756576_a_at

11756984_a_at

11756994_a_at

11756995_a_at

17049443

200852_3p_x_at

200852_x_at

2783

3015741

3015743

3015747

3015748

3015749

3015750

3015751

3015752

3015754

3015757

3015759

3015760

3015761

3015763

3015764

38831_f_at

38832_r_at

8134890

A_23_P82296

GE81483

GO:0003674

GO:0003924

GO:0005246

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005764

GO:0005765

GO:0005773

GO:0005829

GO:0005834

GO:0005886

GO:0005925

GO:0006457

GO:0007165

GO:0007186

GO:0008150

GO:0016020

GO:0019899

GO:0031682

GO:0031982

GO:0032991

GO:0043226

GO:0044297

GO:0044877

GO:0048471

GO:0051020

GO:0070062

ILMN_1658928

M36429_s_at

PH_hs_0029380

TC07000630.hg

g4885282_3p_x_at

Participant Of

hasMember

Other forms of this molecule

GNB2 [plasma membrane]

Unfolded GNB2 [cytosol]

GNB2 [cytosol]

Inferred To

STE4 [cytosol] (Saccharomyces cerevisiae)

git5 [cytosol] (Schizosaccharomyces pombe)

gnb2 [cytosol] (Danio rerio)

GNB2 [cytosol] (Canis familiaris)

GNB2 [cytosol] (Sus scrofa)

gpb-1 [cytosol] (Caenorhabditis elegans)

Gbeta76C [cytosol] (Drosophila melanogaster)

G-protein beta 2 subunit [cytosol] (Mus musculus)

Gnb2 [cytosol] (Rattus norvegicus)

Gbeta13F [cytosol] (Drosophila melanogaster)

Homologues of GNB1 [cytosol] (Drosophila melanogaster)

gpbA [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_005264.2

Target Pathogen

5b354852be737e166372e7f7, 5b354852be737e166372e7ac

OpenTargets

ENSG00000172354

GeneCards

P62879

HPA

ENSG00000172354-GNB2

Ensembl

ENSG00000172354, ENST00000419828, ENST00000427895, ENSP00000305260, ENST00000393924, ENSP00000377503, ENST00000303210, ENSP00000377501, ENSP00000400286, ENST00000393926, ENSP00000390543

PRO

P62879

HMDB Protein

HMDBP08399

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	10
UniProt:Q9NPD8 UBE2T	3	MonoUb-K91,K182-UBE2T [nucleoplasm] (R-HSA-6785362) Ub-C86-UBE2T [nucleoplasm] (R-HSA-8864217) UBE2T [nucleoplasm] (R-HSA-420942)	0.556	3
UniProt:O14933 UBE2L6	2	UBE2L6 [cytosol] (R-HSA-936014) UBE2L6 [nucleoplasm] (R-HSA-5653666)	0.556	3
UniProt:P37840 SNCA	4	SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.556	3
UniProt:Q969M7 UBE2F	3	G76-NEDD8-C116-AcM-UBE2F [cytosol] (R-HSA-8951758) AcM-UBE2F [cytosol] (R-HSA-8951623) UBE2F [cytosol] (R-HSA-947635)	0.556	3
UniProt:P00441 SOD1	5	2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [extracellular region] (R-HSA-350705) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [cytosol] (R-HSA-3299726)	0.556	3
UniProt:Q9NT62 ATG3	2	CysO263-ATG3 [cytosol] (R-HSA-5683569) ATG3 [cytosol] (R-HSA-5671860)	0.556	3
UniProt:P61081 UBE2M	5	G76-NEDD8-C111-AcM-UBE2M [nucleoplasm] (R-HSA-8952508) AcM-UBE2M [nucleoplasm] (R-HSA-8952502) UBE2M [cytosol] (R-HSA-947619) G76-NEDD8-C111-AcM-UBE2M [cytosol] (R-HSA-4419894) AcM-UBE2M [cytosol] (R-HSA-8951627)	0.556	3
UniProt:Q9H0Y0 ATG10	2	GlyK166-ATG10 [cytosol] (R-HSA-5683572) ATG10 [cytosol] (R-HSA-5671733)	0.556	3

Cite Us!