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RNF114 [cytosol]
Stable Identifier
R-HSA-8850894
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase RNF114 ecNumber6.3.2.-/ecNumber, RN114_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF114 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y508 RNF114
Gene Names
RNF114, ZNF228, ZNF313
Chain
chain:1-228
Reference Genes
BioGPS Gene:55905 RNF114
COSMIC (genes):RNF114 RNF114
CTD Gene:55905 RNF114
dbSNP Gene:55905 RNF114
ENSEMBL:ENSG00000124226 RNF114
HGNC:13094 RNF114
KEGG:hsa:55905 RNF114
Monarch:55905 RNF114
NCBI Gene:55905 RNF114
OMIM:612451 RNF114
UCSC:Q9Y508 RNF114
Reference Transcript
RefSeq:NM_018683.3 RNF114
Other Identifiers
11715622_a_at
11715623_s_at
11750214_a_at
16914781
200867_PM_at
200867_at
200868_PM_s_at
200868_s_at
211678_PM_s_at
211678_s_at
38670_at
3888475
3888476
3888482
3888483
3888484
3888485
3888486
3888487
3888488
3888489
3888491
3888492
3888493
3888494
3888495
3888496
3888497
3888498
55905
8063369
A_23_P120458
A_24_P82948
A_24_P82957
GE61598
GO:0000209
GO:0003824
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006511
GO:0007283
GO:0016567
GO:0016740
GO:0022414
GO:0030154
GO:0043226
GO:0046872
GO:0061630
GO:0140096
HMNXSV003002172
Hs.10590.0.A2_3p_at
ILMN_1792078
PH_hs_0022593
TC20000393.hg
g6690233_3p_s_at
g8923897_3p_a_at
Participates
as a member of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
rnf114 [cytosol]
(Danio rerio)
rnf114 [cytosol]
(Xenopus tropicalis)
RNF114 [cytosol]
(Bos taurus)
RNF114 [cytosol]
(Canis familiaris)
RNF114 [cytosol]
(Gallus gallus)
RNF114 [cytosol]
(Mus musculus)
RNF114 [cytosol]
(Rattus norvegicus)
RNF114 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_061153.1
ENSEMBL
ENST00000244061
,
ENSP00000244061
OpenTargets
ENSG00000124226
HPA
ENSG00000124226-RNF114
PRO
Q9Y508
Pharos - Targets
Q9Y508
GlyGen
Q9Y508
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6GPH4 XAF1
1
XAF1 [cytosol]
(R-HSA-1015680)
0.666
8
UniProt:P51668 UBE2D1
3
UBE2D1 [cytosol]
(R-HSA-174236)
UBE2D1 [nucleoplasm]
(R-HSA-174197)
Ub-C85-UBE2D1 [cytosol]
(R-HSA-8864160)
0.621
3
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
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