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RBBP6 [cytosol]
Stable Identifier
R-HSA-8850895
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase RBBP6 ecNumber6.3.2.-/ecNumber, RBBP6_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOBTB GTPase Cycle (Homo sapiens)
RHOBTB1 GTPase cycle (Homo sapiens)
RHOBTB1 binds interacting proteins at the endosome membrane (Homo sapiens)
RHOBTB1 interacting proteins [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
RHOBTB1:GTP:RHOBTB1 interacting proteins [endosome membrane] (Homo sapiens)
RHOBTB1 interacting proteins [cytosol] (Homo sapiens)
RBBP6 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z6E9 RBBP6
Gene Names
RBBP6, P2PR, PACT, RBQ1, My038
Chain
chain:1-1792
Reference Genes
BioGPS Gene:5930 RBBP6
COSMIC (genes):RBBP6 RBBP6
CTD Gene:5930 RBBP6
dbSNP Gene:5930 RBBP6
ENSEMBL:ENSG00000122257 RBBP6
ENSEMBL_homo_sapiens_GENE:ENSG00000122257.20 RBBP6
HGNC:9889 RBBP6
Monarch:5930 RBBP6
NCBI Gene:5930 RBBP6
OMIM:600938 RBBP6
UCSC:Q7Z6E9 RBBP6
Reference Transcript
RefSeq:NM_006910.4 RBBP6
RefSeq:NM_018703.3 RBBP6
RefSeq:NM_032626.5 RBBP6
Other Identifiers
11730916_a_at
11737034_a_at
11743327_a_at
11743328_a_at
11755842_a_at
1552329_PM_at
1552329_at
16817090
205178_PM_s_at
205178_s_at
212781_PM_at
212781_at
212783_PM_at
212783_at
228814_PM_at
228814_at
3253367
3653316
3653318
3653319
3653323
3653326
3653327
3653328
3653329
3653335
3653339
3653340
3653341
3653342
3653345
3653349
3653350
3653351
3653352
3653353
3653355
3653356
3653357
3653358
3653359
3653360
3653361
3653363
3653365
3653366
3653370
3653371
3653372
3653373
3653374
37933_at
38265_at
38266_at
49258_at
49261_i_at
49262_r_at
5930
60424_at
7994161
A_14_P139553
A_23_P363206
GE60097
GE79449
GO:0001701
GO:0003676
GO:0003723
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006260
GO:0006275
GO:0006397
GO:0006511
GO:0006974
GO:0008270
GO:0016071
GO:0016567
GO:0016607
GO:0016740
GO:0019901
GO:0030163
GO:0032991
GO:0035264
GO:0036211
GO:0043226
GO:0046872
GO:0048568
GO:0048856
GO:0061053
GO:0061630
GO:0140096
HMNXSV003002329
HMNXSV003018512
Hs.8991.2.A1_3p_at
Hs.91065.0.S1_3p_at
Hs.91065.0.S2_3p_at
Hs2.374853.1.A1_3p_at
ILMN_1665135
ILMN_1673042
ILMN_2309446
PH_hs_0022899
TC16000262.hg
X85133_at
g5902043_3p_a_at
Participates
as a candidate of
RHOBTB1 interacting proteins [cytosol] (Homo sapiens)
as a member of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
MPE1 [cytosol]
(Saccharomyces cerevisiae)
rbbp6 [cytosol]
(Xenopus tropicalis)
rbpl-1 [cytosol]
(Caenorhabditis elegans)
snama [cytosol]
(Drosophila melanogaster)
RBBP6 [cytosol]
(Bos taurus)
RBBP6 [cytosol]
(Canis familiaris)
RBBP6 [cytosol]
(Dictyostelium discoideum)
RBBP6 [cytosol]
(Gallus gallus)
RBBP6 [cytosol]
(Schizosaccharomyces pombe)
RBBP6 [cytosol]
(Sus scrofa)
Rbbp6 [cytosol]
(Mus musculus)
Rbbp6 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_116015.2
,
NP_061173.1
,
NP_008841.2
OpenTargets
ENSG00000122257
GeneCards
Q7Z6E9
HPA
ENSG00000122257-RBBP6
Ensembl
ENST00000348022
,
ENSP00000390537
,
ENST00000452655
,
ENST00000319715
,
ENSG00000122257
,
ENSP00000370427
,
ENSP00000316291
,
ENST00000381039
,
ENSP00000317872
PRO
Q7Z6E9
Pharos - Targets
Q7Z6E9
PDB
6E5X
,
2C7H
,
2YUR
,
3ZTG
,
2YSA
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q16629 SRSF7
1
SRSF7 [nucleoplasm]
(R-HSA-72029)
0.543
3
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