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RNF217 [cytosol]
Stable Identifier
R-HSA-8850896
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Probable E3 ubiquitin-protein ligase RNF217 ecNumber6.3.2.-/ecNumber, RN217_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF217 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TC41 RNF217
Gene Names
RNF217, C6orf172, IBRDC1, OSTL
Chain
chain:1-542
Reference Genes
BioGPS Gene:154214 RNF217
COSMIC (genes):RNF217 RNF217
CTD Gene:154214 RNF217
dbSNP Gene:154214 RNF217
ENSEMBL:ENSG00000146373 RNF217
ENSEMBL_homo_sapiens_GENE:ENSG00000146373.17 RNF217
HGNC:21487 RNF217
KEGG Gene (Homo sapiens):154214 RNF217
Monarch:154214 RNF217
NCBI Gene:154214 RNF217
OMIM:618592 RNF217
UCSC:Q8TC41 RNF217
Reference Transcript
RefSeq:NM_152553.4 RNF217
RefSeq:NM_001286398.2 RNF217
Other Identifiers
11754566_a_at
154214
17012262
226885_PM_at
226885_at
232100_PM_at
232100_at
235492_PM_at
235492_at
2924254
2924255
2924256
2924263
2924264
2924275
2924284
2924291
2924292
2924296
2924300
2924301
2924302
2924303
2924304
2924305
2924306
2924307
2924308
2924309
2924310
2924311
2924312
2924313
2924314
2924315
2924316
2924317
46998_at
48235_at
57672_at
8121825
84464_at
A_14_P100707
A_14_P105010
A_14_P113209
A_14_P126923
A_23_P353005
A_32_P164203
GE560645
GE861654
GE894841
GO:0000151
GO:0000209
GO:0003824
GO:0004842
GO:0005737
GO:0005829
GO:0006511
GO:0008270
GO:0016020
GO:0016567
GO:0016740
GO:0030163
GO:0031624
GO:0032436
GO:0036211
GO:0046872
GO:0061630
GO:0140096
HMNXSV003028683
Hs.12876.0.A1_3p_at
Hs.288735.0.S1_3p_at
Hs.307526.0.A1_3p_at
ILMN_1722089
ILMN_1854349
PH_hs_0015830
TC06003033.hg
Participates
as a member of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
Rnf217 [cytosol]
(Rattus norvegicus)
rnf217 [cytosol]
(Xenopus tropicalis)
RNF217 [cytosol]
(Bos taurus)
RNF217 [cytosol]
(Canis familiaris)
RNF217 [cytosol]
(Dictyostelium discoideum)
RNF217 [cytosol]
(Gallus gallus)
RNF217 [cytosol]
(Mus musculus)
RNF217 [cytosol]
(Sus scrofa)
Homologues of RNF217 [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_689766.1
,
NP_001273327.1
OpenTargets
ENSG00000146373
GeneCards
Q8TC41
HPA
ENSG00000146373-RNF217
Ensembl
ENST00000521654
,
ENST00000359704
,
ENSG00000146373
,
ENSP00000352734
,
ENSP00000428698
PRO
Q8TC41
Pharos - Targets
Q8TC41
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