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RLIM [cytosol]
Stable Identifier
R-HSA-8850898
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase RLIM ecNumber6.3.2.-/ecNumber, RNF12_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RLIM [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NVW2 RLIM
Gene Names
RLIM, RNF12
Chain
chain:1-624
Reference Genes
BioGPS Gene:51132 RLIM
COSMIC (genes):RLIM RLIM
CTD Gene:51132 RLIM
dbSNP Gene:51132 RLIM
ENSEMBL:ENSG00000131263 RLIM
ENSEMBL_homo_sapiens_GENE:ENSG00000131263.13 RLIM
HGNC:13429 RLIM
KEGG Gene (Homo sapiens):51132 RLIM
Monarch:51132 RLIM
NCBI Gene:51132 RLIM
OMIM:300379 RLIM
UCSC:Q9NVW2 RLIM
Reference Transcript
RefSeq:NM_016120.3 RLIM
RefSeq:NM_183353.2 RLIM
Other Identifiers
11725336_a_at
11725337_a_at
11734798_x_at
11734799_s_at
11748097_x_at
17112198
215823_PM_x_at
215823_x_at
222815_PM_at
222815_at
225416_PM_at
225416_at
3146791
3146795
3593503
3593505
3593507
3593508
3593511
3593513
3593514
3593515
4012867
4012869
4012870
4012871
4012872
4012873
4012874
4012875
4012876
4012877
4012878
4012879
4012880
4012882
4012884
4012885
4012886
4012887
48961_at
51132
57428_at
58275_at
59809_f_at
66461_at
8173613
8173615
A_19_P00809830
A_23_P148484
A_32_P152673
A_33_P3414669
GE55757
GO:0000122
GO:0003714
GO:0003824
GO:0004842
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006325
GO:0006351
GO:0006355
GO:0006511
GO:0016567
GO:0016740
GO:0017053
GO:0030163
GO:0036211
GO:0043226
GO:0045892
GO:0046872
GO:0060816
GO:0061630
GO:0140096
GO:0140110
HMNXSV003013906
Hs.15043.1.A1_3p_at
Hs.15470.0.A2_3p_at
Hs.172182.2.A1_3p_s_at
Hs.283767.0.S1_3p_x_at
ILMN_1727789
ILMN_2254182
ILMN_2335109
PH_hs_0022352
PH_hs_0039727
TC0X001162.hg
Participates
as a member of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
Homologues of RLIM [cytosol]
(Dictyostelium discoideum)
RLIM [cytosol]
(Bos taurus)
RLIM [cytosol]
(Canis familiaris)
RLIM [cytosol]
(Danio rerio)
RLIM [cytosol]
(Dictyostelium discoideum)
RLIM [cytosol]
(Gallus gallus)
RLIM [cytosol]
(Plasmodium falciparum)
RLIM [cytosol]
(Sus scrofa)
rnf12 [cytosol]
(Xenopus tropicalis)
Rlim [cytosol]
(Mus musculus)
Cross References
RefSeq
NP_899196.1
,
NP_057204.2
OpenTargets
ENSG00000131263
GeneCards
Q9NVW2
HPA
ENSG00000131263-RLIM
Ensembl
ENST00000349225
,
ENSG00000131263
,
ENST00000332687
,
ENSP00000253571
,
ENSP00000328059
PRO
Q9NVW2
Pharos - Targets
Q9NVW2
Orphanet
24245
PDB
6W9A
,
6W7Z
,
6W9D
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