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BTN2A2 [plasma membrane]
Stable Identifier
R-HSA-8851047
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Butyrophilin subfamily 2 member A2, BT2A2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Butyrophilin (BTN) family interactions (Homo sapiens)
BTN2A2 binds T cell surface (Homo sapiens)
BTN2A2 [plasma membrane] (Homo sapiens)
BTN2A2:activated T Cell surface [plasma membrane] (Homo sapiens)
BTN2A2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WVV5 BTN2A2
Gene Names
BTN2A2, BT2.2, BTF2
Chain
signal peptide:1-32, chain:33-523
Reference Genes
BioGPS Gene:10385 BTN2A2
COSMIC (genes):BTN2A2 BTN2A2
CTD Gene:10385 BTN2A2
dbSNP Gene:10385 BTN2A2
ENSEMBL:ENSG00000124508 BTN2A2
HGNC:1137 BTN2A2
Monarch:10385 BTN2A2
NCBI Gene:10385 BTN2A2
OMIM:613591 BTN2A2
UCSC:Q8WVV5 BTN2A2
Reference Transcript
RefSeq:XM_011514231.2 BTN2A2
RefSeq:XM_006714953.3 BTN2A2
RefSeq:XM_005248797.3 BTN2A2
RefSeq:NM_001197237.1 BTN2A2
RefSeq:XM_005248798.4 BTN2A2
RefSeq:NM_006995.4 BTN2A2
RefSeq:XM_011514228.2 BTN2A2
RefSeq:NM_181531.2 BTN2A2
RefSeq:NM_001197240.1 BTN2A2
RefSeq:NM_001197239.1 BTN2A2
RefSeq:NM_001197238.1 BTN2A2
RefSeq:XM_017010167.1 BTN2A2
Other Identifiers
10385
11725755_a_at
11749225_a_at
11749226_x_at
11752766_x_at
11754828_a_at
11760484_a_at
11760485_at
1564684_PM_at
1564684_at
17005632
205298_PM_s_at
205298_s_at
205299_PM_s_at
205299_s_at
2899341
2899342
2899343
2899344
2899345
2899346
2899347
2899348
2899349
2899350
2899351
2899352
2899353
2899354
2899355
2899356
2899357
2899358
2899359
2899360
2899361
2899362
2899363
2899364
2899365
2899369
2899371
2899405
2899457
2899463
2899465
8117447
A_14_P116390
A_21_P0000138
A_23_P122439
A_24_P249072
A_24_P337592
A_24_P346210
GE62838
GO:0000082
GO:0001817
GO:0001818
GO:0002376
GO:0005102
GO:0005515
GO:0005886
GO:0009897
GO:0009986
GO:0016020
GO:0043491
GO:0045591
GO:0046007
GO:0050852
GO:0050860
GO:0051898
GO:0070371
GO:0070373
GO:2000134
HMNXSV003030453
Hs.91813.0.S1_3p_a_at
Hs2.376948.1.S1_3p_at
ILMN_1752758
ILMN_2256894
PH_hs_0005100
TC06000185.hg
U90550_at
g6453812_3p_a_at
Participates
as a component of
BTN2A2:activated T Cell surface [plasma membrane] (Homo sapiens)
as an input of
BTN2A2 binds T cell surface (Homo sapiens)
Inferred To
LOC101731445 [plasma membrane]
(Xenopus tropicalis)
LOC100495695 [plasma membrane]
(Xenopus tropicalis)
LOC100486763 [plasma membrane]
(Xenopus tropicalis)
Btn2a2 [plasma membrane]
(Mus musculus)
Btn2a2 [plasma membrane]
(Rattus norvegicus)
LOC100493151 [plasma membrane]
(Xenopus tropicalis)
LOC100492877 [plasma membrane]
(Xenopus tropicalis)
LOC100855640 [plasma membrane]
(Canis familiaris)
btn1a1l [plasma membrane]
(Xenopus tropicalis)
Homologues of BTN2A2 [plasma membrane]
(Xenopus tropicalis)
XB5949738 [plasma membrane]
(Xenopus tropicalis)
BTN2A2 [plasma membrane]
(Bos taurus)
BTN2A2 [plasma membrane]
(Gallus gallus)
BTN2A2 [plasma membrane]
(Sus scrofa)
LOC100496169 [plasma membrane]
(Xenopus tropicalis)
LOC100485074 [plasma membrane]
(Xenopus tropicalis)
btn2a2 [plasma membrane]
(Xenopus tropicalis)
Cross References
OpenTargets
ENSG00000124508
ENSEMBL
ENSP00000419451
,
ENST00000356709
,
ENST00000416795
,
ENST00000469230
,
ENSP00000337117
,
ENSP00000349143
,
ENSP00000394241
,
ENSP00000399308
,
ENST00000482536
,
ENST00000432533
,
ENST00000352867
,
ENSP00000417472
HPA
ENSG00000124508-BTN2A2
PRO
Q8WVV5
Pharos - Targets
Q8WVV5
GlyGen
Q8WVV5
PDB
8IH4
Interactors (51)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P25788 PSMA3
2
PSMA3 [cytosol]
(R-HSA-68728)
PSMA3 [nucleoplasm]
(R-HSA-174323)
0.556
3
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:Q8N5K1 CISD2
0.556
3
UniProt:Q13323 BIK
0.556
3
UniProt:Q9HC36 MRM3
1
RNMTL1 [mitochondrial matrix]
(R-HSA-6793067)
0.556
3
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.556
3
UniProt:O14863 ZNT4
0.556
3
UniProt:Q9H2F3 HSD3B7
1
HSD3B7 [endoplasmic reticulum membrane]
(R-HSA-193441)
0.556
3
UniProt:Q969F0 FATE1
0.556
3
UniProt:O15552 FFAR2
1
FFAR2 [plasma membrane]
(R-HSA-443944)
0.556
3
UniProt:Q9BY50 SEC11C
1
SEC11C [endoplasmic reticulum membrane]
(R-HSA-265065)
0.556
3
UniProt:Q96Q45-2 TMEM237
0.556
5
UniProt:O00623 PEX12
2
PEX12 [cytosol]
(R-HSA-9603782)
PEX12 [peroxisomal membrane]
(R-HSA-8953911)
0.556
3
UniProt:Q3KNW5 SLC10A6
1
SLC10A6 [plasma membrane]
(R-HSA-433091)
0.556
3
UniProt:Q8TED1 GPX8
1
GPX8 [endoplasmic reticulum lumen]
(R-HSA-3341303)
0.556
3
UniProt:Q9Y282 ERGI3
0.556
3
UniProt:O15529 GPR42
0.556
3
UniProt:Q9NUH8 TM14B
0.556
3
UniProt:P21579 SYT1
7
SYT1 [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-372508)
SYT1 [plasma membrane]
(R-HSA-168786)
SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-917741)
SYT1 [clathrin-sculpted glutamate transport vesicle membrane]
(R-HSA-372514)
SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane]
(R-HSA-210536)
SYT1 [synaptic vesicle membrane]
(R-HSA-194789)
SYT1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869113)
0.556
3
UniProt:P43003 SLC1A3
3
SLC1A3 [plasma membrane]
(R-HSA-210520)
SLC1A3 P290R [plasma membrane]
(R-HSA-5625248)
SLC1A3 C186S [plasma membrane]
(R-HSA-5625228)
0.556
3
UniProt:Q7Z7N9 TMEM179B
4
TMEM179B [azurophil granule membrane]
(R-HSA-6799362)
TMEM179B [secretory granule membrane]
(R-HSA-6801009)
TMEM179B [plasma membrane]
(R-HSA-6806263)
TMEM179B [ficolin-1-rich granule membrane]
(R-HSA-6800989)
0.556
3
UniProt:O75712 GJB3
2
GJB3 [plasma membrane]
(R-HSA-9839595)
GJB3 [endoplasmic reticulum membrane]
(R-HSA-190625)
0.556
3
IntAct:EBI-22326698 CCSB ORF ID
0.556
3
UniProt:Q9GZR5 ELOVL4
1
ELOVL4 [endoplasmic reticulum membrane]
(R-HSA-548705)
0.556
3
UniProt:P19397 CD53
3
CD53 [tertiary granule membrane]
(R-HSA-6804799)
CD53 [plasma membrane]
(R-HSA-6804817)
CD53 [specific granule membrane]
(R-HSA-6804793)
0.556
3
UniProt:Q5JX71 F209A
0.556
3
UniProt:Q9NP94 SLC39A2
1
SLC39A2 [plasma membrane]
(R-HSA-442395)
0.556
3
UniProt:P34910-2 P349102
0.556
3
UniProt:P54849 EMP1
0.556
3
UniProt:Q4KMG9 TM52B
0.556
3
UniProt:Q8TAF8 LHFPL5
1
LHFPL5 [plasma membrane]
(R-HSA-9658860)
0.556
3
IntAct:EBI-23184686 CCSB ORF ID
0.556
3
UniProt:Q6ZMD2-2 Q6ZMD22
0.556
3
UniProt:Q9Y320 TMX2
0.556
3
UniProt:Q9NZD1 GPC5D
0.556
3
UniProt:P15941-11 MUC1
0.556
3
UniProt:P11912 CD79A
2
p-Y188,Y199-CD79A [plasma membrane]
(R-HSA-983539)
CD79A [plasma membrane]
(R-HSA-197154)
0.556
3
UniProt:P43628 KIR2DL3
1
KIR2DL3 [plasma membrane]
(R-HSA-3006532)
0.556
3
UniProt:Q13336-2 SLC14A1
0.556
3
UniProt:Q9NRM6 IL17RB
1
IL17RB [plasma membrane]
(R-HSA-447257)
0.527
2
UniProt:Q99679 GPR21
0.527
2
UniProt:Q9Y287 ITM2B
1
ITM2B(244-266) [extracellular region]
(R-HSA-976878)
0.527
2
UniProt:Q9NRJ7 PCDBG
0.527
2
UniProt:Q07001 CHRND
1
CHRND [plasma membrane]
(R-HSA-507847)
0.527
2
UniProt:Q8WWF5 ZNRF4
0.527
2
UniProt:P29016 CD1B
1
CD1B [plasma membrane]
(R-HSA-197793)
0.527
2
UniProt:Q7KYR7 BTN2A1
1
BTN2A1 [plasma membrane]
(R-HSA-8851994)
0.527
2
UniProt:Q9UGM1 CHRNA9
1
CHRNA9 [plasma membrane]
(R-HSA-507827)
0.527
2
UniProt:P54709 ATP1B3
1
ATP1B3 [plasma membrane]
(R-HSA-375073)
0.527
2
UniProt:Q8WW62 TMED6
0.527
2
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