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BTN2A2 [plasma membrane]
Stable Identifier
R-HSA-8851047
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Butyrophilin subfamily 2 member A2, BT2A2_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9Y287 ITM2B
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Butyrophilin (BTN) family interactions (Homo sapiens)
BTN2A2 binds T cell surface (Homo sapiens)
BTN2A2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WVV5 BTN2A2
Gene Names
BTN2A2, BT2.2, BTF2
Chain
signal peptide:1-32, chain:33-523
Reference Genes
BioGPS Gene:10385 BTN2A2
COSMIC (genes):BTN2A2 BTN2A2
CTD Gene:10385 BTN2A2
dbSNP Gene:10385 BTN2A2
ENSEMBL:ENSG00000124508 BTN2A2
ENSEMBL_homo_sapiens_GENE:ENSG00000124508.17 BTN2A2
HGNC:1137 BTN2A2
KEGG Gene (Homo sapiens):10385 BTN2A2
Monarch:10385 BTN2A2
NCBI Gene:10385 BTN2A2
OMIM:613591 BTN2A2
UCSC:Q8WVV5 BTN2A2
Reference Transcript
RefSeq:XM_005248798.4 BTN2A2
RefSeq:NM_001197239.1 BTN2A2
RefSeq:XM_017010167.1 BTN2A2
RefSeq:NM_001197240.1 BTN2A2
RefSeq:NM_006995.4 BTN2A2
RefSeq:XM_011514231.2 BTN2A2
RefSeq:NM_001197237.1 BTN2A2
RefSeq:XM_005248797.3 BTN2A2
RefSeq:NM_001197238.1 BTN2A2
RefSeq:XM_011514228.2 BTN2A2
RefSeq:NM_181531.2 BTN2A2
RefSeq:XM_006714953.3 BTN2A2
Other Identifiers
10385
11725755_a_at
11749225_a_at
11749226_x_at
11752766_x_at
11754828_a_at
17005632
205298_PM_s_at
205298_s_at
205299_PM_s_at
205299_s_at
2899341
2899342
2899343
2899345
2899346
2899347
2899348
2899349
2899350
2899351
2899352
2899353
2899354
2899359
2899360
2899361
2899362
2899363
2899364
2899365
2899405
2899457
2899463
2899465
8117447
A_21_P0000138
A_23_P122439
A_24_P249072
A_24_P337592
A_24_P346210
GE62838
GO:0000082
GO:0000278
GO:0001817
GO:0001818
GO:0002376
GO:0005102
GO:0005515
GO:0005886
GO:0007155
GO:0009897
GO:0009986
GO:0016020
GO:0023052
GO:0030154
GO:0043491
GO:0045591
GO:0046007
GO:0048856
GO:0050852
GO:0050860
GO:0051898
GO:0070371
GO:0070373
GO:2000134
HMNXSV003030453
Hs.91813.0.S1_3p_a_at
ILMN_1752758
ILMN_2256894
PH_hs_0005100
TC06000185.hg
U90550_at
g6453812_3p_a_at
Participates
as a component of
BTN2A2:activated T Cell surface [plasma membrane] (Homo sapiens)
as an input of
BTN2A2 binds T cell surface (Homo sapiens)
Inferred To
LOC101731445 [plasma membrane]
(Xenopus tropicalis)
LOC100495695 [plasma membrane]
(Xenopus tropicalis)
LOC100486763 [plasma membrane]
(Xenopus tropicalis)
Btn2a2 [plasma membrane]
(Mus musculus)
Btn2a2 [plasma membrane]
(Rattus norvegicus)
LOC100493151 [plasma membrane]
(Xenopus tropicalis)
LOC100492877 [plasma membrane]
(Xenopus tropicalis)
LOC100855640 [plasma membrane]
(Canis familiaris)
btn1a1l [plasma membrane]
(Xenopus tropicalis)
Homologues of BTN2A2 [plasma membrane]
(Xenopus tropicalis)
XB5949738 [plasma membrane]
(Xenopus tropicalis)
BTN2A2 [plasma membrane]
(Bos taurus)
BTN2A2 [plasma membrane]
(Gallus gallus)
BTN2A2 [plasma membrane]
(Sus scrofa)
LOC100496169 [plasma membrane]
(Xenopus tropicalis)
LOC100485074 [plasma membrane]
(Xenopus tropicalis)
btn2a2 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001184169.1
,
NP_001184168.1
,
NP_853509.1
,
XP_011512530.1
,
NP_001184166.1
,
XP_006715016.1
,
NP_001184167.1
,
XP_011512533.1
,
XP_005248854.1
,
XP_016865656.1
,
NP_008926.2
,
XP_005248855.1
OpenTargets
ENSG00000124508
HPA
ENSG00000124508-BTN2A2
GeneCards
Q8WVV5
Ensembl
ENSP00000349143
,
ENST00000432533
,
ENSG00000124508
,
ENST00000356709
,
ENST00000352867
,
ENSP00000419451
,
ENST00000482536
,
ENSP00000417472
,
ENSP00000337117
,
ENST00000416795
,
ENST00000469230
,
ENSP00000399308
,
ENSP00000394241
PRO
Q8WVV5
Pharos - Targets
Q8WVV5
PDB
8IH4
Interactors (51)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13336-2 SLC14A1
0.556
3
UniProt:P43628 KIR2DL3
1
KIR2DL3 [plasma membrane]
(R-HSA-3006532)
0.556
3
UniProt:P11912 CD79A
2
p-Y188,Y199-CD79A [plasma membrane]
(R-HSA-983539)
CD79A [plasma membrane]
(R-HSA-197154)
0.556
3
UniProt:P15941-11 MUC1
0.556
3
UniProt:Q9NZD1 GPC5D
0.556
3
UniProt:Q9Y320 TMX2
0.556
3
UniProt:Q6ZMD2-2 Q6ZMD22
0.556
3
IntAct:EBI-23184686 CCSB ORF ID
0.556
3
UniProt:Q8TAF8 LHFPL5
1
LHFPL5 [plasma membrane]
(R-HSA-9658860)
0.556
3
UniProt:Q4KMG9 TM52B
0.556
3
UniProt:P54849 EMP1
0.556
3
UniProt:P34910-2 P349102
0.556
3
UniProt:Q9NP94 SLC39A2
1
SLC39A2 [plasma membrane]
(R-HSA-442395)
0.556
3
UniProt:Q5JX71 F209A
0.556
3
UniProt:P25788 PSMA3
2
PSMA3 [nucleoplasm]
(R-HSA-174323)
PSMA3 [cytosol]
(R-HSA-68728)
0.556
3
UniProt:P19397 CD53
3
CD53 [specific granule membrane]
(R-HSA-6804793)
CD53 [plasma membrane]
(R-HSA-6804817)
CD53 [tertiary granule membrane]
(R-HSA-6804799)
0.556
3
UniProt:Q9GZR5 ELOVL4
1
ELOVL4 [endoplasmic reticulum membrane]
(R-HSA-548705)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
IntAct:EBI-22326698 CCSB ORF ID
0.556
3
UniProt:O75712 GJB3
2
GJB3 [plasma membrane]
(R-HSA-9839595)
GJB3 [endoplasmic reticulum membrane]
(R-HSA-190625)
0.556
3
UniProt:Q7Z7N9 TMEM179B
4
TMEM179B [ficolin-1-rich granule membrane]
(R-HSA-6800989)
TMEM179B [secretory granule membrane]
(R-HSA-6801009)
TMEM179B [plasma membrane]
(R-HSA-6806263)
TMEM179B [azurophil granule membrane]
(R-HSA-6799362)
0.556
3
UniProt:P43003 SLC1A3
3
SLC1A3 C186S [plasma membrane]
(R-HSA-5625228)
SLC1A3 P290R [plasma membrane]
(R-HSA-5625248)
SLC1A3 [plasma membrane]
(R-HSA-210520)
0.556
3
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.556
3
UniProt:Q9NUH8 TM14B
0.556
3
UniProt:O15529 GPR42
0.556
3
UniProt:Q9Y282 ERGI3
0.556
3
UniProt:Q8TED1 GPX8
1
GPX8 [endoplasmic reticulum lumen]
(R-HSA-3341303)
0.556
3
UniProt:Q3KNW5 SLC10A6
1
SLC10A6 [plasma membrane]
(R-HSA-433091)
0.556
3
UniProt:O00623 PEX12
2
PEX12 [cytosol]
(R-HSA-9603782)
PEX12 [peroxisomal membrane]
(R-HSA-8953911)
0.556
3
UniProt:Q96Q45-2 TMEM237
0.556
5
UniProt:Q9BY50 SEC11C
1
SEC11C [endoplasmic reticulum membrane]
(R-HSA-265065)
0.556
3
UniProt:Q969F0 FATE1
0.556
3
UniProt:Q9H2F3 HSD3B7
1
HSD3B7 [endoplasmic reticulum membrane]
(R-HSA-193441)
0.556
3
UniProt:O14863 ZNT4
0.556
3
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.556
3
UniProt:Q9HC36 MRM3
1
RNMTL1 [mitochondrial matrix]
(R-HSA-6793067)
0.556
3
UniProt:Q13323 BIK
0.556
3
UniProt:Q8N5K1 CISD2
0.556
3
UniProt:O15552 FFAR2
1
FFAR2 [plasma membrane]
(R-HSA-443944)
0.556
3
UniProt:P21579 SYT1
7
SYT1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869113)
SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane]
(R-HSA-210536)
SYT1 [synaptic vesicle membrane]
(R-HSA-194789)
SYT1 [clathrin-sculpted glutamate transport vesicle membrane]
(R-HSA-372514)
SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-917741)
SYT1 [plasma membrane]
(R-HSA-168786)
SYT1 [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-372508)
0.556
3
UniProt:Q9NRM6 IL17RB
1
IL17RB [plasma membrane]
(R-HSA-447257)
0.527
2
UniProt:Q99679 GPR21
0.527
2
UniProt:Q9Y287 ITM2B
1
ITM2B(244-266) [extracellular region]
(R-HSA-976878)
0.527
2
UniProt:Q9NRJ7 PCDBG
0.527
2
UniProt:Q7KYR7 BTN2A1
1
BTN2A1 [plasma membrane]
(R-HSA-8851994)
0.527
2
UniProt:Q07001 CHRND
1
CHRND [plasma membrane]
(R-HSA-507847)
0.527
2
UniProt:Q8WWF5 ZNRF4
0.527
2
UniProt:P29016 CD1B
1
CD1B [plasma membrane]
(R-HSA-197793)
0.527
2
UniProt:Q8WW62 TMED6
0.527
2
UniProt:P54709 ATP1B3
1
ATP1B3 [plasma membrane]
(R-HSA-375073)
0.527
2
UniProt:Q9UGM1 CHRNA9
1
CHRNA9 [plasma membrane]
(R-HSA-507827)
0.527
2
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