CCR8 binds CCL1

Stable Identifier
R-HSA-8851352
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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CCR8 is the receptor for CCL1 (Roos et al. 1997, Tiffany et al. 1997)Goya et al. 1998, Dairaghi et al. 1999). CCL1-induced mobilization of intracellular calcium was inhibited by pertussis toxin, suggesting that CCR8 is coupled to the Gi class of Galpha subunits (Tiffany et al. 1997, Goya et al. 1998)
Literature References
PubMed ID Title Journal Year
9207005 Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309

Murphy, PM, Locati, M, Tiffany, HL, Combadiere, C, Gao, JL, Modi, W, Pease, J, Bonner, TI, Lautens, LL

J Exp Med 1997
Participants
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Orthologous Events
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