Reactome | ENTPD5 [extracellular region]

ENTPD5 [extracellular region]

Stable Identifier

R-HSA-8851371

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Ectonucleoside triphosphate diphosphohydrolase 5, NTPDase 5, CD39L4, CD39 antigen-like 4, PCPH

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Parasitic Infection Pathways (Homo sapiens)
    - Leishmania infection (Homo sapiens)
      - Cell recruitment (pro-inflammatory response) (Homo sapiens)
        
        Purinergic signaling in leishmaniasis infection (Homo sapiens)
        
        NTPDase5 hydrolyzes nucleoside diphosphates (Homo sapiens)
        
        NPTDase5:Ca2+,Mg2+ [extracellular region] (Homo sapiens)
        
        ENTPD5 [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:O75356 ENTPD5

Gene Names

ENTPD5, CD39L4, PCPH

Chain

signal peptide:1-24, chain:25-428

Reference Genes

BioGPS Gene:957 ENTPD5

COSMIC (genes):ENTPD5 ENTPD5

CTD Gene:957 ENTPD5

dbSNP Gene:957 ENTPD5

ENSEMBL:ENSG00000187097 ENTPD5

ENSEMBL_homo_sapiens_GENE:ENSG00000187097.13 ENTPD5

HGNC:3367 ENTPD5

KEGG Gene (Homo sapiens):957 ENTPD5

Monarch:957 ENTPD5

NCBI Gene:957 ENTPD5

OMIM:603162 ENTPD5

UCSC:O75356 ENTPD5

Reference Transcript

Other Identifiers

11727176_a_at

16794606

205757_PM_at

205757_at

226594_PM_at

226594_at

3571670

3571671

3571672

3571673

3571674

3571675

3571676

3571677

3571678

3571679

3571682

3571683

3571684

3571685

3571686

3571688

3571690

3571691

3571693

3571695

3571698

3571701

3571702

3571703

3571712

3571713

3571714

40666_at

48904_at

7980080

957

GE79880

GO:0003824

GO:0004382

GO:0005515

GO:0005576

GO:0005615

GO:0005783

GO:0006011

GO:0006256

GO:0006457

GO:0006486

GO:0006487

GO:0009134

GO:0016020

GO:0016787

GO:0017110

GO:0036211

GO:0036384

GO:0043226

GO:0043262

GO:0045134

GO:0051084

GO:0055086

GO:1901135

GO:1990003

HMNXSV003017233

HMNXSV003048170

Hs.285290.1.A1_3p_at

ILMN_1745849

PH_hs_0022470

PH_hs_0038369

TC14001302.hg

TC14002083.hg

g4557426_3p_at

p28676

Participates

as a component of

NPTDase5:Ca2+,Mg2+ [extracellular region] (Homo sapiens)

Inferred To

Entpd5 [extracellular region] (Mus musculus)

Entpd5 [extracellular region] (Rattus norvegicus)

GDA1 [extracellular region] (Saccharomyces cerevisiae)

ENTPD5 [extracellular region] (Bos taurus)

ENTPD5 [extracellular region] (Canis familiaris)

ENTPD5 [extracellular region] (Drosophila melanogaster)

ENTPD5 [extracellular region] (Gallus gallus)

ENTPD5 [extracellular region] (Plasmodium falciparum)

ENTPD5 [extracellular region] (Sus scrofa)

gdp1 [extracellular region] (Schizosaccharomyces pombe)

uda-1 [extracellular region] (Caenorhabditis elegans)

Cross References

RefSeq

XP_016877302.1, NP_001308916.1, NP_001308917.1, NP_001240.1, NP_001308914.1, NP_001308915.1, XP_005268281.1

OpenTargets

ENSG00000187097

IntEnz

3.6.1.6

GeneCards

O75356

HPA

ENSG00000187097-ENTPD5

Ensembl

ENSG00000187097, ENSP00000335246, ENST00000334696

PRO

O75356

Pharos - Targets

O75356

HMDB Protein

HMDBP00879

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3