GPR183 [plasma membrane]

Stable Identifier
R-HSA-8851676
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
G-protein coupled receptor 183, GP183_HUMAN
Locations in the PathwayBrowser
Expand all
General
GPR183 (originally called EBI2) binds the oxysterol 7alpha,25-dihydroxycholesterol (7a,25-OHC) (Hannedouche et al. 2011, Liu et al. 2011). GPR183 is believed to played a key role in regulating B cell migration and responses (Gatto et al. 2009, Pereira et al. 2009, Yi et al. 2012, Sun & Liu 2015). It signals via Gi (Rosenkilde et al. 2006).
External Reference Information
External Reference
UniProt:P32249 GPR183
Gene Names
GPR183, EBI2
Chain
chain:1-361
Reference Genes
BioGPS Gene:1880 GPR183
COSMIC (genes):GPR183 GPR183
CTD Gene:1880 GPR183
dbSNP Gene:1880 GPR183
ENSEMBL:ENSG00000169508 GPR183
ENSEMBL_homo_sapiens_GENE:ENSG00000169508.7 GPR183
HGNC:3128 GPR183
KEGG Gene (Homo sapiens):1880 GPR183
Monarch:1880 GPR183
NCBI Gene:1880 GPR183
OMIM:605741 GPR183
UCSC:P32249 GPR183
Reference Transcript
Other Identifiers
11727428_at
11758555_s_at
16780592
1880
205419_PM_at
205419_at
3522663
3522664
3522665
3522669
7972557
931_at
A_23_P25566
GE57589
GO:0002250
GO:0002312
GO:0002313
GO:0002376
GO:0002407
GO:0004930
GO:0005886
GO:0006955
GO:0006959
GO:0007165
GO:0007186
GO:0008142
GO:0008289
GO:0010818
GO:0016020
GO:0023052
GO:0030154
GO:0030316
GO:0030595
GO:0030890
GO:0036145
GO:0048856
GO:0048870
GO:0060089
GO:0060326
GO:0061470
GO:0070374
GO:2000458
HMNXSV003030157
ILMN_1798706
ILMN_2168217
L08177_at
PH_hs_0000092
PH_hs_0040414
TC13000829.hg
g4826705_3p_at
g4826705_3p_x_at
Participates
as an input of
as a component of
Inferred To
GPR183 [plasma membrane] (Bos taurus)
GPR183 [plasma membrane] (Canis familiaris)
GPR183 [plasma membrane] (Gallus gallus)
GPR183 [plasma membrane] (Mus musculus)
GPR183 [plasma membrane] (Rattus norvegicus)
GPR183 [plasma membrane] (Sus scrofa)
gpr183.2 [plasma membrane] (Xenopus tropicalis)
gpr183a [plasma membrane] (Danio rerio)
Cross References
RefSeq
Guide to Pharmacology - Targets
81
OpenTargets
HPA
ZINC - Substances
GeneCards
ZINC target
Ensembl
PRO
Pharos - Targets
ZINC - Predictions - Purchasable
PDB
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