Reactome | BTN2A1 [plasma membrane]

BTN2A1 [plasma membrane]

Stable Identifier

R-HSA-8851994

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Butyrophilin subfamily 2 member A1, BT2A1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P20036 HLA-DPA1

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External Reference Information

External Reference

UniProt:Q7KYR7 BTN2A1

Gene Names

BTN2A1, BT2.1, BTF1

Chain

signal peptide:1-28, chain:29-527

Reference Genes

BioGPS Gene:11120 BTN2A1

COSMIC (genes):BTN2A1 BTN2A1

CTD Gene:11120 BTN2A1

dbSNP Gene:11120 BTN2A1

ENSEMBL:ENSG00000112763 BTN2A1

ENSEMBL_homo_sapiens_GENE:ENSG00000112763.17 BTN2A1

ENSEMBL_homo_sapiens_GENE:ENSG00000292170.1 BTN2A1

HGNC:1136 BTN2A1

KEGG Gene (Homo sapiens):11120 BTN2A1

Monarch:11120 BTN2A1

NCBI Gene:11120 BTN2A1

OMIM:613590 BTN2A1

UCSC:Q7KYR7 BTN2A1

Reference Transcript

Other Identifiers

11120

11719050_a_at

11747874_x_at

17005707

203944_PM_x_at

203944_x_at

211256_PM_x_at

211256_x_at

215493_PM_x_at

215493_x_at

244063_PM_at

244063_at

2899349

2899360

2899395

2899396

2899405

2899438

2899439

2899440

2899442

2899443

2899444

2899445

2899451

2899452

2899454

2899455

2899456

2899457

2899462

2899463

2899464

2899465

2899466

2899467

2899468

2899469

2899470

2899472

32673_at

8117485

81693_at

A_21_P0004859

A_21_P0004860

A_21_P0005112

A_23_P501634

A_24_P934528

A_33_P3332885

GE536946

GE62839

GO:0001817

GO:0002376

GO:0003674

GO:0005102

GO:0005515

GO:0005886

GO:0006629

GO:0009897

GO:0016020

GO:0023052

GO:0050852

HMNXSV003011868

HMNXSV003052672

HMNXSV003057427

Hs.159028.0.S1_3p_at

Hs.169963.2.S1_3p_a_at

ILMN_1783392

ILMN_2364852

PH_hs_0010142

PH_hs_0040494

TC06000189.hg

TC06002648.hg

U90543_at

U90543_s_at

p23411

p33634

Participates

as a component of

BTN2A1:CD209 [plasma membrane] (Homo sapiens)

as an input of

BTN2A1 binds DC-SIGN (Homo sapiens)

Inferred To

Homologues of BTN2A1 [plasma membrane] (Xenopus tropicalis)

LOC101731445 [plasma membrane] (Xenopus tropicalis)

BTN2A1 [plasma membrane] (Gallus gallus)

LOC100495695 [plasma membrane] (Xenopus tropicalis)

LOC107131749 [plasma membrane] (Bos taurus)

LOC100486763 [plasma membrane] (Xenopus tropicalis)

Btn2a2 [plasma membrane] (Mus musculus)

Btn2a2 [plasma membrane] (Rattus norvegicus)

LOC100493151 [plasma membrane] (Xenopus tropicalis)

LOC100492877 [plasma membrane] (Xenopus tropicalis)

LOC100855640 [plasma membrane] (Canis familiaris)

btn1a1l [plasma membrane] (Xenopus tropicalis)

XB5949738 [plasma membrane] (Xenopus tropicalis)

BTN2A2 [plasma membrane] (Sus scrofa)

LOC100496169 [plasma membrane] (Xenopus tropicalis)

LOC100485074 [plasma membrane] (Xenopus tropicalis)

btn2a2 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001184162.1, NP_510961.1, NP_001184163.1, NP_008980.1

OpenTargets

ENSG00000112763

GeneCards

Q7KYR7

HPA

ENSG00000112763-BTN2A1

Ensembl

ENSP00000419043, ENSP00000416945, ENST00000541522, ENST00000312541, ENSP00000443909, ENST00000429381, ENST00000469185, ENSG00000112763, ENSP00000312158

PRO

Q7KYR7

Pharos - Targets

Q7KYR7

PDB

8DFY, 8JYC, 8JYE, 8DFX, 8DFW

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:A8MVW0 F1712			0.527	2
UniProt:Q9NZ56 FMN2			0.527	2
UniProt:B0FP48 UPK3L			0.527	2
UniProt:Q8NEN9 PDZD8			0.527	3
UniProt:Q15042 RAB3GAP1	2	RAB3GAP1 [endoplasmic reticulum membrane] (R-HSA-508581) RAB3GAP1 [cytosol] (R-HSA-8877982)	0.527	2
UniProt:Q5SVS4 KMCP1			0.527	2
UniProt:Q9NV66 TYW1	1	TYW1 [cytoplasm] (R-HSA-6782884)	0.527	3
UniProt:Q8IWF6 DENND6A	1	DENND6A [cytosol] (R-HSA-8876587)	0.527	2
UniProt:Q9H1E5 TMX4			0.527	3
UniProt:P03886 MT-ND1	1	MT-ND1 [mitochondrial inner membrane] (R-HSA-60551)	0.527	2
UniProt:Q9H2G9 BLZF1	1	BLZF1 [Golgi membrane] (R-HSA-2422372)	0.527	2
UniProt:P29016 CD1B	1	CD1B [plasma membrane] (R-HSA-197793)	0.527	2
UniProt:Q969R8 ITFG2	1	ITFG2 [lysosomal membrane] (R-HSA-9638231)	0.527	2
UniProt:Q8WVV5 BTN2A2	1	BTN2A2 [plasma membrane] (R-HSA-8851047)	0.527	2
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.527	2
UniProt:P22059 OSBP	1	OSBP [cytosol] (R-HSA-429725)	0.527	3
UniProt:A5A3E0 POTEF			0.527	2
UniProt:P20036 HLA-DPA1	9	HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (R-HSA-2130667) HLA class II histocompatibility antigen, DP alpha chain precursor [ER to Golgi transport vesicle membrane] (R-HSA-2130739) HLA class II histocompatibility antigen, DP alpha chain precursor [Golgi membrane] (R-HSA-2214387) HLA class II histocompatibility antigen, DP alpha chain precursor [trans-Golgi network membrane] (R-HSA-2130337) HLA class II histocompatibility antigen, DP alpha chain precursor [transport vesicle membrane] (R-HSA-2130648) HLA class II histocompatibility antigen, DP alpha chain precursor [clathrin-coated endocytic vesicle membrane] (R-HSA-2130485) HLA class II histocompatibility antigen, DP alpha chain precursor [endocytic vesicle membrane] (R-HSA-2130435) HLA class II histocompatibility antigen, DP alpha chain precursor [lysosomal membrane] (R-HSA-2130639) HLA class II histocompatibility antigen, DP alpha chain precursor [plasma membrane] (R-HSA-197586)	0.527	2

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