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pS-ADRB2 [plasma membrane]
Stable Identifier
R-HSA-8852158
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Beta-2 adrenoceptor, RecName: Full=Beta-2 adrenergic receptor; AltName: Full=Beta-2 adrenoreceptor; Short=Beta-2 adrenoceptor;
GN Name=ADRB2; Synonyms=ADRB2R, B2AR;
OS Homo sapiens, ADRB2_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
ADRB2 in ADRB2:GRK complex is phosphorylated (Homo sapiens)
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
ADRB2:Catecholamine binds ARRB1, ARRB2 (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine:ARRB1,ARRB2 [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
BAR domain proteins recruit dynamin (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
ARBB recruits GPCRs into clathrin-coated pits (Homo sapiens)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
ARRB bind GPCRs (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
Clathrin recruits PIK3C2A (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
Endophilins recruit synaptojanins to the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
SNX9 recruits components of the actin polymerizing machinery (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
CLASP proteins:cargo [plasma membrane] (Homo sapiens)
ARRB:ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
ARRB-binding GPCRs [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
pS-ADRB2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P07550 ADRB2
Gene Names
ADRB2, ADRB2R, B2AR
Chain
chain:1-413
Reference Genes
BioGPS Gene:154 ADRB2
COSMIC (genes):ADRB2 ADRB2
CTD Gene:154 ADRB2
dbSNP Gene:154 ADRB2
ENSEMBL:ENSG00000169252 ADRB2
HGNC:286 ADRB2
KEGG:hsa:154 ADRB2
Monarch:154 ADRB2
NCBI Gene:154 ADRB2
UCSC:P07550 ADRB2
Reference Transcript
RefSeq:NM_000024.5 ADRB2
Other Identifiers
11728728_s_at
154
16990848
206170_PM_at
206170_at
2834747
2834748
2834749
2834750
2834751
2834752
2834753
2834754
2834755
610_at
8109086
A_14_P117388
A_14_P200154
A_23_P145024
GE80303
GO:0001540
GO:0001993
GO:0002024
GO:0002025
GO:0002028
GO:0003012
GO:0003013
GO:0004930
GO:0004935
GO:0004941
GO:0005515
GO:0005634
GO:0005764
GO:0005768
GO:0005769
GO:0005773
GO:0005794
GO:0005886
GO:0006351
GO:0006355
GO:0006366
GO:0006898
GO:0006939
GO:0006940
GO:0007166
GO:0007171
GO:0007186
GO:0007188
GO:0007189
GO:0008179
GO:0008333
GO:0009409
GO:0010008
GO:0010739
GO:0015459
GO:0016020
GO:0016192
GO:0016324
GO:0019899
GO:0030154
GO:0030501
GO:0030669
GO:0031410
GO:0031649
GO:0040015
GO:0042802
GO:0042803
GO:0043226
GO:0043235
GO:0043410
GO:0044877
GO:0045453
GO:0045744
GO:0045944
GO:0045986
GO:0050873
GO:0051380
GO:0060089
GO:0061885
GO:0065003
GO:0071875
GO:0071880
GO:0071902
GO:0097746
GO:0098772
GO:0098992
GO:0120162
GO:1901098
GO:1904504
GO:1904646
GO:1990911
GO:2000481
GO:2000969
HMNXSV003031336
ILMN_1695590
J02960_cds1_s_at
M15169_at
PH_hs_0000339
TC05000814.hg
g13162366_3p_at
Participates
as a component of
pS-ADRB2:Catecholamine:GRK [plasma membrane] (Homo sapiens)
pS-ADRB2:Catecholamine [plasma membrane] (Homo sapiens)
Other forms of this molecule
ADRB2 [plasma membrane]
PolyUb-ADRB2 [endosome membrane]
ADRB2 [endosome membrane]
pS-ADRB2 [clathrin-coated endocytic vesicle membrane]
Inferred To
Homologues of pS-ADRB2 [plasma membrane]
(Drosophila melanogaster)
phospho-Adrb2 [plasma membrane]
(Mus musculus)
phospho-Adrb2 [plasma membrane]
(Rattus norvegicus)
phospho-Octbeta3R [plasma membrane]
(Drosophila melanogaster)
phospho-adrb2 [plasma membrane]
(Xenopus tropicalis)
phospho-adrb2b [plasma membrane]
(Danio rerio)
phospho-Octbeta1R [plasma membrane]
(Drosophila melanogaster)
phospho-ADRB2 [plasma membrane]
(Bos taurus)
phospho-ADRB2 [plasma membrane]
(Canis familiaris)
phospho-ADRB2 [plasma membrane]
(Gallus gallus)
phospho-ADRB2 [plasma membrane]
(Sus scrofa)
phospho-Octbeta2R [plasma membrane]
(Drosophila melanogaster)
Modified Residues
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_000015.1
ZINC - World Drugs
ADRB2_HUMAN
Guide to Pharmacology - Targets
29
OpenTargets
ENSG00000169252
ENSEMBL
ENSP00000305372
,
ENST00000305988
ZINC - FDA approved
ADRB2_HUMAN
ZINC - Substances
ADRB2_HUMAN
ZINC - Biogenic
ADRB2_HUMAN
ZINC target
P07550
PRO
P07550
GlyGen
P07550
PDB
8GE3
,
8UNW
,
8UHB
,
8GE1
,
7BZ2
,
6PRZ
,
8UNY
,
8UO4
,
2R4R
,
8GE8
,
8JJ8
,
8GE7
,
8GG7
,
8GEE
,
8GEG
,
7XKA
,
8GDZ
,
8GEF
,
6MXT
,
8GG3
,
8GEH
,
8UNM
,
5D5B
,
6PS3
,
8GGW
,
8GH0
,
8GGE
,
6PS1
,
8GFX
,
8GGB
,
8GGK
,
8GFW
,
8GGP
,
6KR8
,
8UNV
,
3NY8
,
3KJ6
,
8GE2
,
8JJO
,
2RH1
,
3PDS
,
8GGZ
,
6OBA
,
8UO2
,
8UNS
,
8GFV
,
8GED
,
8UO1
,
8GEA
,
6NI3
,
4LDE
,
8UO0
,
6PS4
,
8GGO
,
8GGV
,
4LDO
,
8GGF
,
5JQH
,
6PS2
,
8GFZ
,
8GGS
,
3SN6
,
8GGJ
,
1GQ4
,
7DHR
,
8UNU
,
8GE5
,
7DHI
,
8UO3
,
8GGY
,
6E67
,
4QKX
,
8UNQ
,
5D6L
,
2R4S
,
8GE6
,
8GG5
,
8GG6
,
8GEC
,
8GEI
,
5X7D
,
8UNP
,
8GG1
,
7XK9
,
8UNO
,
8GG2
,
6PS0
,
5D5A
,
8GGM
,
8GGU
,
8GGN
,
4GBR
,
8GGA
,
8GGQ
,
8GGR
,
8GFY
,
3P0G
,
8UNX
,
8GE4
,
8JJL
,
8UNR
,
8UNZ
,
8UNT
,
8GGX
,
3D4S
,
3NYA
,
8GE9
,
8GEJ
,
8GG4
,
8GEB
,
8UNN
,
8GG0
,
6PS5
,
6PS6
,
8UNL
,
8GGL
,
8GGT
,
8GG9
,
8GGC
,
6N48
,
8GGI
,
8GH1
,
8GG8
,
3NY9
,
4LDL
ZINC - Investigational
ADRB2_HUMAN
ZINC - Metabolites
ADRB2_HUMAN
HPA
ENSG00000169252-ADRB2
Pharos - Targets
P07550
ZINC - Predictions - Purchasable
ADRB2_HUMAN
HMDB Protein
HMDBP01634
Interactors (30)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96B67 ARRD3
0.681
6
UniProt:P07550 ADRB2
5
ADRB2 [plasma membrane]
(R-HSA-390647)
pS-ADRB2 [plasma membrane]
(R-HSA-8852158)
PolyUb-ADRB2 [endosome membrane]
(R-HSA-6783066)
ADRB2 [endosome membrane]
(R-HSA-6783036)
pS-ADRB2 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869143)
0.657
4
UniProt:Q5TCQ9 MAGI3
0.619
9
UniProt:P04896 GNAS2
0.612
4
UniProt:P54311 Gnb1
3
Gnb1 [cytosol]
(R-RNO-6814412)
G-protein beta 1 subunit [plasma membrane]
(R-RNO-421797)
Gnb1 [photoreceptor disc membrane]
(R-RNO-55373)
0.612
4
UniProt:P63212 GNG2
1
GNG2 [plasma membrane]
(R-BTA-9717212)
0.612
4
UniProt:P12931 SRC
6
MyrG-p-Y419-SRC [plasma membrane]
(R-HSA-1810408)
MyrG,p-Y530-SRC [plasma membrane]
(R-HSA-377598)
MyrG-SRC [plasma membrane]
(R-HSA-8876922)
p-Y419-SRC [cytosol]
(R-HSA-8964276)
SRC [cytosol]
(R-HSA-9628701)
p-Y419-SRC [nucleoplasm]
(R-HSA-8937690)
0.611
3
UniProt:P30542 ADORA1
1
ADORA1 [plasma membrane]
(R-HSA-418941)
0.61
5
UniProt:P32121 ARRB2
3
ARRB2 [cytosol]
(R-HSA-416464)
PolyUb-ARRB2 [cytosol]
(R-HSA-6783000)
ARRB2 [endocytic vesicle membrane]
(R-HSA-9910881)
0.608
3
UniProt:O14745 NHRF1
0.558
6
UniProt:A0AVK6 E2F8
1
E2F8 [nucleoplasm]
(R-HSA-8952990)
0.556
3
UniProt:Q9ULD4-2 Q9ULD42
0.556
3
UniProt:Q15486 GUSP1
0.556
3
UniProt:Q9NSI6-4 BRWD1
0.556
3
UniProt:Q9UII2 ATIF1
0.556
3
UniProt:Q8N0U2 TMM61
0.556
3
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.556
3
UniProt:Q658K8 EF1DL
0.556
3
UniProt:Q5M9N0-2 CCDC158
0.556
3
UniProt:Q8WVD3 RNF138
1
RNF138 [cytosol]
(R-HSA-976008)
0.556
3
UniProt:Q9NR21-5 PARP11
0.556
3
UniProt:Q9H0X6 RN208
0.556
3
UniProt:Q15910-2 EZH2
0.556
3
UniProt:O00472 ELL2
1
ELL2 [nucleoplasm]
(R-HSA-6807506)
0.556
3
UniProt:Q5T0J7-2 TEX35
0.556
3
UniProt:P61978 HNRNPK
2
HNRNPK [nucleoplasm]
(R-HSA-71945)
polySUMO2-K422-HNRNPK [nucleoplasm]
(R-HSA-4570532)
0.508
2
UniProt:Q99685 MGLL
3
MGLL [plasma membrane]
(R-HSA-426055)
MGLL [lipid droplet]
(R-HSA-163567)
MGLL [endoplasmic reticulum membrane]
(R-HSA-1500589)
0.508
2
UniProt:Q14232 EIF2B1
1
EIF2B1 [cytosol]
(R-HSA-72517)
0.463
2
UniProt:P02686 MBP
1
MBP [cytosol]
(R-HSA-9614770)
0.454
2
UniProt:P04156 PRNP
2
PRNP [cytosol]
(R-HSA-9617597)
PRNP [plasma membrane]
(R-HSA-375060)
0.454
2
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