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p-S435-GTSE1 [nucleoplasm]
Stable Identifier
R-HSA-8852332
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser for interactor UniProt:Q9UJY5 GGA1
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
G2/M Checkpoints (Homo sapiens)
GTSE1 binds TP53 (Homo sapiens)
p-S435-GTSE1 [nucleoplasm] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
The role of GTSE1 in G2/M progression after G2 checkpoint (Homo sapiens)
GTSE1 binds TP53 (Homo sapiens)
p-S435-GTSE1 [nucleoplasm] (Homo sapiens)
GTSE1 translocates to the nucleus (Homo sapiens)
p-S435-GTSE1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYZ3 GTSE1
Gene Names
GTSE1
Chain
chain:1-739
Reference Genes
BioGPS Gene:51512 GTSE1
COSMIC (genes):GTSE1 GTSE1
CTD Gene:51512 GTSE1
dbSNP Gene:51512 GTSE1
ENSEMBL:ENSG00000075218 GTSE1
ENSEMBL_homo_sapiens_GENE:ENSG00000075218.19 GTSE1
HGNC:13698 GTSE1
KEGG Gene (Homo sapiens):51512 GTSE1
Monarch:51512 GTSE1
NCBI Gene:51512 GTSE1
OMIM:607477 GTSE1
UCSC:Q9NYZ3 GTSE1
Reference Transcript
RefSeq:XM_005261627.3 GTSE1
RefSeq:XM_017028815.1 GTSE1
RefSeq:NM_016426.6 GTSE1
Other Identifiers
11736082_a_at
11736083_x_at
16931384
204315_PM_s_at
204315_s_at
204318_PM_s_at
204318_s_at
211040_PM_x_at
211040_x_at
215942_PM_s_at
215942_s_at
39374_at
39375_g_at
3949056
3949059
3949061
3949062
3949063
3949064
3949067
3949068
3949070
3949078
3949080
3949082
3949083
3949085
3949087
3949088
3949089
3949090
3949091
39872_at
51512
63703_s_at
8073858
A_14_P135311
A_23_P57588
GE82125
GO:0000278
GO:0003674
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005856
GO:0005874
GO:0005881
GO:0006977
GO:0007017
GO:0008017
GO:0008092
GO:0015630
GO:0016020
GO:0023052
GO:0043226
HMNXSV003027674
Hs.122552.0.S1_3p_s_at
Hs.122552.2.S1_3p_s_at
TC22000394.hg
g13623450_3p_s_at
p33936
Participates
as an output of
GTSE1 translocates to the nucleus (Homo sapiens)
as an input of
GTSE1 binds TP53 (Homo sapiens)
as a component of
p-S435-GTSE1:PolyUb-TP53 Tetramer [nucleoplasm] (Homo sapiens)
Other forms of this molecule
GTSE1 [cytosol]
p-S435-GTSE1 [cytosol]
p-T513,T526-GTSE1 [cytosol]
Inferred To
phospho-p-S435-GTSE1 [nucleoplasm]
(Gallus gallus)
phospho-GTSE1 [nucleoplasm]
(Bos taurus)
phospho-GTSE1 [nucleoplasm]
(Canis familiaris)
phospho-GTSE1 [nucleoplasm]
(Sus scrofa)
phospho-gtse1 [nucleoplasm]
(Danio rerio)
phospho-gtse1 [nucleoplasm]
(Xenopus tropicalis)
phospho-Gtse1 [nucleoplasm]
(Mus musculus)
phospho-Gtse1 [nucleoplasm]
(Rattus norvegicus)
Modified Residues
Name
O-phospho-L-serine at 435
Coordinate
435
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_016884304.1
,
NP_057510.4
,
XP_005261684.1
OpenTargets
ENSG00000075218
GeneCards
Q9NYZ3
HPA
ENSG00000075218-GTSE1
Ensembl
ENSG00000075218
,
ENST00000454366
,
ENSP00000415430
PRO
Q9NYZ3
Pharos - Targets
Q9NYZ3
PDB
6QNN
,
6QNP
Interactors (16)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q709F0 ACAD11
1
ACAD11 [mitochondrial inner membrane]
(R-HSA-5695987)
0.643
3
UniProt:Q96FJ0 STAMBPL1
1
STAMBPL1 [cytosol]
(R-HSA-6783264)
0.643
3
UniProt:O95630 STAMBP
1
STAMBP [cytosol]
(R-HSA-5693063)
0.643
3
UniProt:P53350 PLK1
4
PLK1 [nucleoplasm]
(R-HSA-156720)
p-T210-PLK1 [cytosol]
(R-HSA-3000318)
p-T210-PLK1 [nucleoplasm]
(R-HSA-3002800)
PLK1 [cytosol]
(R-HSA-164603)
0.571
6
UniProt:Q00610 CLTC
10
CLTC [trans-Golgi network membrane]
(R-HSA-5333703)
CLTC [cytosol]
(R-HSA-8856820)
CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-ALK(1058-1620) fusion [cytosol]
(R-HSA-9710852)
CLTC(2-1634)insV-p-7Y-ALK(1059-1620) fusion [cytosol]
(R-HSA-9710854)
CLTC [plasma membrane]
(R-HSA-2980668)
CLTC [lysosomal membrane]
(R-HSA-2980660)
CLTC [clathrin-coated endocytic vesicle membrane]
(R-HSA-5138450)
CLTC [endolysosome membrane]
(R-HSA-8870827)
CLTC(2-1634)insV-ALK(1059-1620) fusion [cytosol]
(R-HSA-9710853)
CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9710835)
0.564
3
UniProt:Q9UJY5 GGA1
2
GGA1 [early endosome membrane]
(R-HSA-8854136)
GGA1 [endosome membrane]
(R-HSA-5692930)
0.544
2
UniProt:Q01968 OCRL
4
OCRL [Golgi membrane]
(R-HSA-434339)
OCRL [cytoplasmic vesicle membrane]
(R-HSA-434214)
OCRL [plasma membrane]
(R-HSA-3769049)
OCRL [cytosol]
(R-HSA-1806196)
0.527
2
UniProt:Q13492 PICALM
3
PICALM [cytosol]
(R-HSA-8867593)
PICALM [cytoplasmic vesicle membrane]
(R-HSA-429812)
PICALM [Golgi membrane]
(R-HSA-434341)
0.527
2
UniProt:Q5SZD1 CF141
0.527
2
UniProt:Q06190 P2R3A
0.527
2
UniProt:P01350 GAST
1
GAST(76-92) [extracellular region]
(R-HSA-870266)
0.527
2
UniProt:Q92466 DDB2
3
PolyUb-DDB2 [nucleoplasm]
(R-HSA-6783035)
DDB2 [nucleoplasm]
(R-HSA-53491)
PAR-DDB2 [nucleoplasm]
(R-HSA-5696654)
0.527
2
UniProt:P56539 CAV3
1
CAV3 [plasma membrane]
(R-HSA-1368135)
0.527
2
UniProt:Q8WTP9 XAGE3
0.527
2
UniProt:Q13492-2 PICALM
0.527
2
UniProt:Q9Y664 KPTN
1
KPTN [lysosomal membrane]
(R-HSA-9638238)
0.527
2
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