There will be a maintenance on OICR IT systems starting Friday Dec 15 at 6PM EST until midnight Sunday Dec 17; Reactome will be affected by this downtime

Service under maintenance from Friday Dec 15 at 6PM EST until midnight Sunday Dec 17

GTSE1 promotes translocation of TP53 to the cytosol

Stable Identifier
R-HSA-8852351
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Binding of GTSE1 to TP53 (p53) in the nucleus promotes translocation of TP53 to the cytosol. This process is dependent on the nuclear export signal (NES) of GTSE1 (Monte et al. 2004).

Literature References
PubMed ID Title Journal Year
14707141 hGTSE-1 expression stimulates cytoplasmic localization of p53 J. Biol. Chem. 2004
Participants
Participant Of
Event Information
Orthologous Events