FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane]

Stable Identifier
R-HSA-8853131
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
23175443 Oncogenic FGFR3 gene fusions in bladder cancer

Knowles, MA, Williams, SV, Hurst, CD

Hum. Mol. Genet. 2013
23558953 Identification of targetable FGFR gene fusions in diverse cancers

Kalyana-Sundaram, S, Chinnaiyan, AM, Wang, R, Tomlins, SA, Ateeq, B, Cao, X, Cheng, AJ, Rhodes, DR, Hussain, MH, Kunju, LP, Lonigro, RJ, Robinson, DR, Sadis, S, Talpaz, M, Lin, SF, Pienta, KJ, Feng, FY, Roychowdhury, S, Vats, P, Wu, YM, Wyngaard, P, Su, F, Khazanov, N, Siddiqui, J, Zalupski, MM

Cancer Discov 2013
External Reference Information
External Reference
Gene Names
FGFR3, JTK4
Chain
signal peptide:1-22, chain:23-806
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 18 to 522 at 761 from UniProt:Q9UHR4 BAIAP2L1
Coordinate
761
Disease
Name Identifier Synonyms
bladder carcinoma DOID:4007 carcinoma of urinary bladder, carcinoma bladder, carcinoma OF BLADDER, carcinoma of bladder (disorder), carcinoma bladder
Cross References
COSMIC
Interactors (52)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P08238 HSP90AB1  6 0.667 4
 UniProt:O95674 CDS2  1 0.659 4
 UniProt:Q7Z7J5 DPPA2  1 0.556 3
 UniProt:Q9Y2Y0 ARL2BP  2 0.556 3
 UniProt:P62333 PSMC6  2 0.556 3
 UniProt:Q6NXG1 ESRP1  3 0.556 3
 UniProt:P23771 GATA3  2 0.556 3
 UniProt:Q96EZ8 MCRS1  1 0.556 3
 UniProt:P22415 USF1  2 0.556 3
 UniProt:Q06547-2 GABPB1  1 0.556 3
 UniProt:P38936 CDKN1A  5 0.556 3
 UniProt:Q96T60 PNKP  1 0.556 3
 UniProt:Q99075 HBEGF  8 0.556 3
 UniProt:Q9GZQ8 MAP1LC3B  3 0.556 3
 UniProt:Q04206 RELA  7 0.556 3
 UniProt:P10809 HSPD1  6 0.556 3
 UniProt:P05412 JUN  4 0.556 3
 UniProt:Q8N3R9 MPP5  2 0.556 3
 UniProt:P41134 ID1  1 0.556 3
 UniProt:Q99743 NPAS2  2 0.556 3
 UniProt:Q06323 PSME1  1 0.556 3
 UniProt:P55318 FOXA3  1 0.556 3
 UniProt:Q9NZH6 IL37  6 0.556 3
 UniProt:P17275 JUNB  1 0.556 3
 UniProt:Q16621 NFE2  1 0.556 3
 UniProt:Q00994 BEX3  1 0.556 3
 UniProt:Q9BVC3 DSCC1  1 0.556 3
 UniProt:Q9UJU6 DBNL  7 0.556 3
 UniProt:Q8WUX9 CHMP7  2 0.556 3
 UniProt:Q13573 SNW1  1 0.556 3
 UniProt:P24941 CDK2  5 0.556 3
 UniProt:Q8N5V2 NGEF  2 0.556 3
 UniProt:Q06547-3 GABPB1  1 0.556 3
 UniProt:P01106 MYC  2 0.556 3
 UniProt:Q6IAA8 LAMTOR1  5 0.556 3
 UniProt:Q6N021 TET2  1 0.556 3
 UniProt:Q9UKV8 AGO2  2 0.556 3
 UniProt:O15534 PER1  4 0.556 3
 UniProt:Q9UBX5 FBLN5  1 0.556 3
 UniProt:Q9BXU0 TEX12  1 0.556 3
 UniProt:Q86WV5 TEN1  1 0.556 3
 UniProt:O14544 SOCS6  1 0.556 3
 UniProt:Q15814 TBCC  1 0.556 3
 UniProt:P22692 IGFBP4  5 0.556 3
 UniProt:P62244 RPS15A  2 0.556 3
 UniProt:Q13352 ITGB3BP  2 0.556 3
 UniProt:Q9H2A9 CHST8  1 0.556 3
 UniProt:P19388 POLR2E  2 0.556 3
 UniProt:O14641 DVL2  5 0.556 3
 UniProt:O43504 LAMTOR5  1 0.556 3
 UniProt:Q07869 PPARA  2 0.556 3
 UniProt:A0AVK6 E2F8  1 0.556 3
Cite Us!