Reactome | MANBA [lysosomal lumen]

MANBA [lysosomal lumen]

Stable Identifier

R-HSA-8853711

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

lysosomal lumen

Synonyms

Beta-mannosidase ecNumber3.2.1.25/ecNumber, MANBA_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O00462 MANBA

Gene Names

MANBA, MANB1

Chain

signal peptide:1-17, chain:18-879

Reference Genes

BioGPS Gene:4126 MANBA

COSMIC (genes):MANBA MANBA

CTD Gene:4126 MANBA

dbSNP Gene:4126 MANBA

ENSEMBL:ENSG00000109323 MANBA

ENSEMBL_homo_sapiens_GENE:ENSG00000109323.11 MANBA

HGNC:6831 MANBA

KEGG Gene (Homo sapiens):4126 MANBA

Monarch:4126 MANBA

NCBI Gene:4126 MANBA

OMIM:609489 MANBA

UCSC:O00462 MANBA

Reference Transcript

RefSeq:NM_005908.3 MANBA

Other Identifiers

11750126_a_at

11758386_s_at

16978444

203778_PM_at

203778_at

2779898

2779899

2779900

2779901

2779902

2779907

2779908

2779909

2779910

2779912

2779918

2779920

2779923

2779926

2779927

2779928

2779931

2779932

2779938

2779941

2779942

2779943

2779958

2779959

37472_at

4126

8102006

A_23_P258698

GE59271

GO:0003824

GO:0004553

GO:0004567

GO:0005537

GO:0005764

GO:0005773

GO:0005886

GO:0005975

GO:0006516

GO:0008152

GO:0009313

GO:0016787

GO:0016798

GO:0030163

GO:0031410

GO:0035577

GO:0036211

GO:0043202

GO:0043226

GO:1901135

HMNXSV003007484

ILMN_1800733

PH_hs_0024586

TC04001430.hg

g5174522_3p_at

Other forms of this molecule

MANBA [plasma membrane]

MANBA [azurophil granule membrane]

Inferred To

MANBA [lysosomal lumen] (Bos taurus)

MANBA [lysosomal lumen] (Caenorhabditis elegans)

MANBA [lysosomal lumen] (Canis familiaris)

MANBA [lysosomal lumen] (Dictyostelium discoideum)

MANBA [lysosomal lumen] (Gallus gallus)

MANBA [lysosomal lumen] (Mus musculus)

MANBA [lysosomal lumen] (Rattus norvegicus)

MANBA [lysosomal lumen] (Sus scrofa)

manba [lysosomal lumen] (Danio rerio)

manba [lysosomal lumen] (Xenopus tropicalis)

beta-Man [lysosomal lumen] (Drosophila melanogaster)

Cross References

RefSeq

NP_005899.3

OpenTargets

ENSG00000109323

GeneCards

O00462

ZINC - Substances

MANBA_HUMAN

HPA

ENSG00000109323-MANBA

Ensembl

ENSG00000109323, ENST00000647097, ENSP00000495247

ZINC target

O00462

PRO

O00462

Pharos - Targets

O00462

ZINC - Predictions - Purchasable

MANBA_HUMAN

Orphanet

16375

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95968 SG1D1			0.527	2
UniProt:Q17RF5 ODAPH			0.527	2
UniProt:P59665 DEFA1	9	omega-N-(ADP-ribosyl)-L-arginine-DEFA1(65-94) [extracellular region] (R-HSA-1972397) DEFA1(20-65) [Golgi lumen] (R-HSA-8864970) DEFA1(66-94) [Golgi lumen] (R-HSA-975663) DEFA1(20-94) [Golgi lumen] (R-HSA-1467282) DEFA1(1-94) [Golgi lumen] (R-HSA-1467215) DEFA1(66-94) [extracellular region] (R-HSA-1461998) DEFA1(65-94) [extracellular region] (R-HSA-1462022) DEFA1(65-94) [azurophil granule lumen] (R-HSA-1470053) DEFA1(66-94) [azurophil granule lumen] (R-HSA-1470038)	0.527	2
UniProt:O75173 ADAMTS4	4	ADAMTS4 [extracellular region] (R-HSA-2533998) ADAMTS4 [endoplasmic reticulum lumen] (R-HSA-5173253) glc-fuc-ADAMTS4 [endoplasmic reticulum lumen] (R-HSA-5172994) O-fuc-ADAMTS4 [endoplasmic reticulum lumen] (R-HSA-5173144)	0.527	2
UniProt:A4D1T9 PRS37			0.527	2

Cite Us!