Proteasome-mediated degradation of PolyUb-FBXL7

Stable Identifier
R-HSA-8854071
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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FBXL7, polyubiquitinated by the FBXL18-containing SCF complex, is degraded by the proteasome (Liu et al. 2015).

Literature References
PubMed ID Title Journal Year
25654763 F-box protein Fbxl18 mediates polyubiquitylation and proteasomal degradation of the pro-apoptotic SCF subunit Fbxl7

Liu, Y, Lear, T, Zhao, Y, Zhao, J, Zou, C, Chen, BB, Mallampalli, RK

Cell Death Dis 2015
Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
endopeptidase activity of 26S proteasome [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created