Reactome | RABGAP1 [cytosol]

RABGAP1 [cytosol]

Stable Identifier

R-HSA-8854144

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Rab GTPase-activating protein 1, RBGP1_HUMAN, TBC1D11, GAPCenA

Locations in the PathwayBrowser for interactor UniProt:Q9UJY5 GGA1

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External Reference Information

External Reference

UniProt:Q9Y3P9 RABGAP1

Gene Names

RABGAP1, HSPC094

Chain

chain:1-1069

Reference Genes

BioGPS Gene:23637 RABGAP1

COSMIC (genes):RABGAP1 RABGAP1

CTD Gene:23637 RABGAP1

dbSNP Gene:23637 RABGAP1

ENSEMBL:ENSG00000011454 RABGAP1

ENSEMBL_homo_sapiens_GENE:ENSG00000011454.18 RABGAP1

HGNC:17155 RABGAP1

KEGG Gene (Homo sapiens):23637 RABGAP1

Monarch:23637 RABGAP1

NCBI Gene:23637 RABGAP1

OMIM:615882 RABGAP1

UCSC:Q9Y3P9 RABGAP1

Reference Transcript

Other Identifiers

11743684_a_at

11743685_a_at

11749520_a_at

17088838

204028_PM_s_at

204028_s_at

213313_PM_at

213313_at

23637

3188303

3188309

3188310

3188319

3188320

3188321

3188324

3188325

3188327

3188329

3188331

3188332

3188333

3188339

3188340

3188342

3188358

3188360

3188362

3188365

3188366

3188368

3188375

3188376

3188381

3188382

3188383

3188385

3188386

3188387

3188388

35289_at

8157700

A_14_P110666

A_21_P0006371

A_24_P252575

A_33_P3411991

GE55202

GO:0005096

GO:0005515

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0005875

GO:0007049

GO:0008092

GO:0015631

GO:0031267

GO:0043087

GO:0043226

GO:0098772

HMNXSV003006359

HMNXSV003018934

HMNXSV003022678

ILMN_2061950

PH_hs_0003618

TC09000627.hg

g12232372_3p_a_at

p26920

p30025

Participates

as a component of

RABGAP1:RAB6:GTP [Golgi membrane] (Homo sapiens)

as an input of

TBC1D11 binds RAB6 (Homo sapiens)

Inferred To

GAPcenA [cytosol] (Drosophila melanogaster)

RABGAP1 [cytosol] (Bos taurus)

RABGAP1 [cytosol] (Gallus gallus)

tbc-11 [cytosol] (Caenorhabditis elegans)

Rabgap1 [cytosol] (Mus musculus)

Rabgap1 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

XP_011516743.1, XP_016870057.1, NP_036329.3, XP_016870058.1, XP_011516742.1, XP_016870056.1

OpenTargets

ENSG00000011454

GeneCards

Q9Y3P9

HPA

ENSG00000011454-RABGAP1

Ensembl

ENSP00000362751, ENST00000373647, ENSP00000414386, ENSG00000011454, ENST00000456584

PRO

Q9Y3P9

Pharos - Targets

Q9Y3P9

PDB

4NC6

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5R372 RBG1L			0.564	3
UniProt:Q9NRI5 DISC1			0.553	2
UniProt:P41587 VIPR2	1	VIPR2 [plasma membrane] (R-HSA-420227)	0.527	3
UniProt:P31146 CORO1A	1	CORO1A [cytosol] (R-HSA-9636432)	0.527	3
UniProt:P48059 LIMS1	1	LIMS1 [cytosol] (R-HSA-432859)	0.527	2
UniProt:Q9H2F9 CCD68			0.527	2
UniProt:P09017 HOXC4	1	HOXC4 [nucleoplasm] (R-HSA-5617871)	0.527	3
UniProt:P43631 KIR2DS2	1	KIR2DS2 [plasma membrane] (R-HSA-199534)	0.527	2
UniProt:Q9Y3C0 WASC3			0.527	3
UniProt:Q9H813 PACC1			0.527	2
UniProt:Q9UJY5 GGA1	2	GGA1 [early endosome membrane] (R-HSA-8854136) GGA1 [endosome membrane] (R-HSA-5692930)	0.527	3
UniProt:Q9H0R8 GABARAPL1	3	GABARAPL1 [autophagosome membrane] (R-HSA-5683637) GABARAPL1(1-117) [cytosol] (R-HSA-5682659) GABARAPL1 [cytosol] (R-HSA-5671757)	0.499	2
UniProt:P40763 STAT3	12	Unfolded STAT3 [cytosol] (R-HSA-6813811) p-STAT3 [nucleoplasm] (R-HSA-8983188) p-STAT3 [cytosol] (R-HSA-8982823) AcK685- p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701435) p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701429) p-S727-STAT3 [cytosol] (R-HSA-198705) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-Y705-STAT3 [nucleoplasm] (R-HSA-9027589) p-Y705-STAT3 [cytosol] (R-HSA-8983130) STAT3 [cytosol] (R-HSA-539044) p-Y705-STAT3 [cytosol] (R-HSA-914048) p-Y705-STAT3 [nucleoplasm] (R-HSA-1112554)	0.488	2

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