TBC1D11 binds RAB6

Stable Identifier
R-HSA-8854303
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Rab6 is associated with Golgi and trans-Golgi (TGN) membranes in interphase and regulates a retrograde transport route connecting early endosomes to the endoplasmic reticulum (ER). TBC domain family, member 11 (TBC1D11 also referred as GAPCENA is a Rab GTPase and directly binds Rab6 via its N-terminal PTB domain (Cuif et al. 1999, Miserey-Lenkei et al. 2006).

Literature References
PubMed ID Title Journal Year
10202141 Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome

Cuif, MH, Possmayer, F, Zander, H, Bordes, N, Jollivet, F, Couedel-Courteille, A, Janoueix-Lerosey, I, Langsley, G, Bornens, M, Goud, B

EMBO J. 1999
16395330 A role for the Rab6A' GTPase in the inactivation of the Mad2-spindle checkpoint

Miserey-Lenkei, S, Cou√ędel-Courteille, A, del Nery, E, Bardin, S, Piel, M, Racine, V, Sibarita, JB, Perez, F, Bornens, M, Goud, B

EMBO J. 2006
Participants
Participant Of
hasEvent
Orthologous Events
Authored
Created