IL22:IL22RA1:JAK1 binds IL10RB:TYK2

Stable Identifier
R-HSA-8854645
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
IL10RB:TYK2 receptor complex binds IL22:IL22RA1:JAK1 receptor complex, IL22RA1:IL22 binds IL10RB
Locations in the PathwayBrowser
Summation

Temporal models suggest that binding of Interleukin?22 (IL22) to Interleukin?22 receptor subunit alpha 1 (IL22RA1) creates a surface that is bound by the extracellular region of Interleukin?10 receptor beta chain (IL10RB) (Li et al. 2004, Bleicher et al. 2008).

Literature References
PubMed ID Title Journal Year
15120653 Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2

Li, J, Tomkinson, KN, Tan, XY, Wu, P, Yan, G, Spaulding, V, Deng, B, Annis-Freeman, B, Heveron, K, Zollner, R, De Zutter, G, Wright, JF, Crawford, TK, Liu, W, Jacobs, KA, Wolfman, NM, Ling, V, Pittman, DD, Veldman, GM, Fouser, LA

Int. Immunopharmacol. 2004
Participants
Participant Of
Orthologous Events
Authored
Reviewed