FLT3LG dimer:FLT3 binds FLT3

Stable Identifier
R-HSA-8854736
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Binding of FLT3LG to monomeric FLT3 induces receptor dimerization (Verstraete et al. 2011, Grafone et al. 2012).

Literature References
PubMed ID Title Journal Year
21389326 Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex

Verstraete, K, Vandriessche, G, Januar, M, Elegheert, J, Shkumatov, AV, Desfosses, A, Van Craenenbroeck, K, Svergun, DI, Gutsche, I, Vergauwen, B, Savvides, SN

Blood 2011
Participants
Participant Of
Orthologous Events
Authored
Reviewed