Reactome | HLA-H [Golgi membrane]

HLA-H [Golgi membrane]

Stable Identifier

R-HSA-8855895

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Putative HLA class I histocompatibility antigen, alpha chain H, HLAH_HUMAN

Locations in the PathwayBrowser

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Immune System (Homo sapiens)

- Adaptive Immune System (Homo sapiens)
  - Class I MHC mediated antigen processing & presentation (Homo sapiens)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
      - Expression of peptide bound class I MHC on cell surface (Homo sapiens)
        
        Antigen peptide bound class I MHC [Golgi membrane] (Homo sapiens)
        
        monoglucosylated MHC class I HC [Golgi membrane] (Homo sapiens)
        
        Class I MHC heavy chain (MHC HC) [Golgi membrane] (Homo sapiens)
        
        HLA-H [Golgi membrane] (Homo sapiens)
      - Journey of cargo through Golgi complex (Homo sapiens)
        
        Antigen peptide bound class I MHC [Golgi membrane] (Homo sapiens)
        
        monoglucosylated MHC class I HC [Golgi membrane] (Homo sapiens)
        
        Class I MHC heavy chain (MHC HC) [Golgi membrane] (Homo sapiens)
        
        HLA-H [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P01893 HLA-H

Gene Names

HLA-H, HLAH

Chain

signal peptide:1-24, chain:25-362

Reference Genes

HGNC:4965 HLA-H

OMIM:142800 HLA-H

UCSC:P01893 HLA-H

Participates

as a member of

Class I MHC heavy chain (MHC HC) [Golgi membrane] (Homo sapiens)

Other forms of this molecule

HLA-H [phagocytic vesicle membrane]

HLA-H [recycling endosome membrane]

HLA-H [early endosome membrane]

HLA-H [ER to Golgi transport vesicle membrane]

HLA-H [plasma membrane]

HLA-H [azurophil granule membrane]

HLA-H [lumenal side of endoplasmic reticulum membrane]

Inferred To

mhc1laa [Golgi membrane] (Danio rerio)

LOC100513601 [Golgi membrane] (Sus scrofa)

H2-M10.6l [Golgi membrane] (Rattus norvegicus)

H2-M3 [Golgi membrane] (Mus musculus)

H2-Q6 [Golgi membrane] (Mus musculus)

RT1-M1-5 [Golgi membrane] (Rattus norvegicus)

mhc1zba [Golgi membrane] (Danio rerio)

BFIV21 [Golgi membrane] (Gallus gallus)

RT1-CE14 [Golgi membrane] (Rattus norvegicus)

ENSRNOG00000069480 [Golgi membrane] (Rattus norvegicus)

H2-M10.6 [Golgi membrane] (Mus musculus)

SLA-8 [Golgi membrane] (Sus scrofa)

H2-M2 [Golgi membrane] (Mus musculus)

RT1-M1-4 [Golgi membrane] (Rattus norvegicus)

RT1-M1-2 [Golgi membrane] (Rattus norvegicus)

DLA88 [Golgi membrane] (Canis familiaris)

DLA-12 [Golgi membrane] (Canis familiaris)

RT1-N3 [Golgi membrane] (Rattus norvegicus)

H2-M10.1 [Golgi membrane] (Mus musculus)

SLA-7 [Golgi membrane] (Sus scrofa)

mhc1zda [Golgi membrane] (Danio rerio)

H2-M1 [Golgi membrane] (Mus musculus)

RT1-M2 [Golgi membrane] (Rattus norvegicus)

H2-M9 [Golgi membrane] (Mus musculus)

RT1-M5 [Golgi membrane] (Rattus norvegicus)

mhc1zca [Golgi membrane] (Danio rerio)

RT1-CE16 [Golgi membrane] (Rattus norvegicus)

RT1-M10-1 [Golgi membrane] (Rattus norvegicus)

SLA-2 [Golgi membrane] (Sus scrofa)

H2-T22 [Golgi membrane] (Mus musculus)

H2-M10.4 [Golgi membrane] (Mus musculus)

H2-K1 [Golgi membrane] (Mus musculus)

mhc1uba [Golgi membrane] (Danio rerio)

ENSRNOG00000064836 [Golgi membrane] (Rattus norvegicus)

RT1-S3 [Golgi membrane] (Rattus norvegicus)

mhc1uma [Golgi membrane] (Danio rerio)

RT1-M3-1 [Golgi membrane] (Rattus norvegicus)

RT1-CE2 [Golgi membrane] (Rattus norvegicus)

RT1-O1l1 [Golgi membrane] (Rattus norvegicus)

H2-M10.3 [Golgi membrane] (Mus musculus)

RT1-CE10 [Golgi membrane] (Rattus norvegicus)

H2-Q1 [Golgi membrane] (Mus musculus)

RT1-CE1 [Golgi membrane] (Rattus norvegicus)

H2-M11 [Golgi membrane] (Mus musculus)

mhc1zea [Golgi membrane] (Danio rerio)

AABR07044308.2 [Golgi membrane] (Rattus norvegicus)

H2-M10.2 [Golgi membrane] (Mus musculus)

H2-M5 [Golgi membrane] (Mus musculus)

SLA-3 [Golgi membrane] (Sus scrofa)

class I MHC B7 [Golgi membrane] (Bos taurus)

class I MHC B7 [Golgi membrane] (Canis familiaris)

class I MHC B7 [Golgi membrane] (Gallus gallus)

class I MHC B7 [Golgi membrane] (Mus musculus)

class I MHC B7 [Golgi membrane] (Sus scrofa)

H2-D1 [Golgi membrane] (Mus musculus)

BF1 [Golgi membrane] (Gallus gallus)

H2-Q2 [Golgi membrane] (Mus musculus)

H2-M10.5 [Golgi membrane] (Mus musculus)

H2-Q10 [Golgi membrane] (Mus musculus)

H2-Q4 [Golgi membrane] (Mus musculus)

H2-T23 [Golgi membrane] (Mus musculus)

Homologues of class I MHC B7 [Golgi membrane] (Bos taurus)

Homologues of class I MHC B7 [Golgi membrane] (Canis familiaris)

Homologues of class I MHC B7 [Golgi membrane] (Danio rerio)

Homologues of class I MHC B7 [Golgi membrane] (Gallus gallus)

Homologues of class I MHC B7 [Golgi membrane] (Mus musculus)

Homologues of class I MHC B7 [Golgi membrane] (Rattus norvegicus)

Homologues of class I MHC B7 [Golgi membrane] (Sus scrofa)

AABR07044362.1 [Golgi membrane] (Rattus norvegicus)

mhc1zfa [Golgi membrane] (Danio rerio)

DLA-79 [Golgi membrane] (Canis familiaris)

LOC119876868 [Golgi membrane] (Canis familiaris)

H2-Q7 [Golgi membrane] (Mus musculus)

H2-T3 [Golgi membrane] (Mus musculus)

SLA-6 [Golgi membrane] (Sus scrofa)

Cross References

OpenTargets

ENSG00000206341

PRO

P01893

Pharos - Targets

P01893

GlyGen

P01893

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.558	2

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