Reactome | RNF185 [endoplasmic reticulum membrane]

RNF185 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-8861819

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

E3 ubiquitin-protein ligase RNF185 ecNumber6.3.2.-/ecNumber, RN185_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96GF1 RNF185

Gene Names

RNF185

Chain

chain:1-192

Reference Genes

BioGPS Gene:91445 RNF185

COSMIC (genes):RNF185 RNF185

CTD Gene:91445 RNF185

dbSNP Gene:91445 RNF185

ENSEMBL:ENSG00000138942 RNF185

HGNC:26783 RNF185

KEGG:hsa:91445 RNF185

Monarch:91445 RNF185

NCBI Gene:91445 RNF185

OMIM:620096 RNF185

UCSC:Q96GF1 RNF185

Reference Transcript

Other Identifiers

11716735_s_at

11756017_a_at

16929148

17123724

17123726

224750_PM_at

224750_at

2784234

2784235

2784237

2784238

2784239

3942806

3942812

3942813

3942814

3942816

3942817

3942818

3942819

3942821

3942822

3942823

3942824

3942825

3942826

3942827

3942828

3942829

57146_at

8072454

91445

A_14_P133375

A_23_P103062

GO:0002376

GO:0003824

GO:0005515

GO:0005739

GO:0005741

GO:0005783

GO:0005789

GO:0006511

GO:0006914

GO:0016567

GO:0016740

GO:0030163

GO:0036503

GO:0043130

GO:0043226

GO:0043231

GO:0044314

GO:0044322

GO:0044390

GO:0044877

GO:0045087

GO:0045089

GO:0046872

GO:0051607

GO:0051865

GO:0055085

GO:0060340

GO:0061630

GO:0098542

GO:0140096

GO:1901135

GO:1904294

GO:1904380

HMNXSV003032350

Hs.279535.1.S1_3p_at

ILMN_1691293

PH_hs_0028411

TC22000223.hg

TC22001071.hg

Participates

as a member of

Inferred To

Rnf185 [endoplasmic reticulum membrane] (Mus musculus)

Rnf185 [endoplasmic reticulum membrane] (Rattus norvegicus)

rnf185 [endoplasmic reticulum membrane] (Danio rerio)

rnf185 [endoplasmic reticulum membrane] (Xenopus tropicalis)

RNF185 [endoplasmic reticulum membrane] (Bos taurus)

RNF185 [endoplasmic reticulum membrane] (Gallus gallus)

RNF185 [endoplasmic reticulum membrane] (Sus scrofa)

rnf-5 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

sordd1 [endoplasmic reticulum membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENSP00000427755, ENST00000266252, ENSP00000320508, ENST00000326132, ENST00000518626, ENSP00000266252

OpenTargets

ENSG00000138942

IntEnz

2.3.2.27

HPA

ENSG00000138942-RNF185

PRO

Q96GF1

Pharos - Targets

Q96GF1

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P51668 UBE2D1	3	UBE2D1 [cytosol] (R-HSA-174236) UBE2D1 [nucleoplasm] (R-HSA-174197) Ub-C85-UBE2D1 [cytosol] (R-HSA-8864160)	0.666	4
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.569	3
UniProt:O75915 ARL6IP5	1	ARL6IP5 [cytosol] (R-HSA-2980942)	0.556	3