Reactome | TOR1A [cytosol]

TOR1A [cytosol]

Stable Identifier

R-HSA-8862858

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Torsin-1A, TOR1A_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O14656 TOR1A

Gene Names

TOR1A, DQ2, DYT1, TA, TORA

Chain

signal peptide:1-20, chain:21-332

Reference Genes

COSMIC (genes):TOR1A TOR1A

dbSNP Gene:1861 TOR1A

ENSEMBL:ENSG00000136827 TOR1A

Participates

as a component of

TOR1A hexamer [cytosol] (Homo sapiens)

Inferred To

TOR1A [cytosol] (Bos taurus)

TOR1A [cytosol] (Caenorhabditis elegans)

TOR1A [cytosol] (Canis familiaris)

TOR1A [cytosol] (Danio rerio)

TOR1A [cytosol] (Dictyostelium discoideum)

TOR1A [cytosol] (Drosophila melanogaster)

TOR1A [cytosol] (Gallus gallus)

TOR1A [cytosol] (Mus musculus)

TOR1A [cytosol] (Sus scrofa)

TOR1A [cytosol] (Xenopus tropicalis)

Tor1a [cytosol] (Rattus norvegicus)

Homologues of TOR1A [cytosol] (Danio rerio)

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.556	3
UniProt:P22692 IGFBP4	5	IGFBP4 [extracellular region] (R-HSA-381421) IGFBP4 [endoplasmic reticulum lumen] (R-HSA-8956754) p-IGFBP4 [endoplasmic reticulum lumen] (R-HSA-8957038) IGFBP4(157-237) [extracellular region] (R-HSA-381510) IGFBP4(22-156) [extracellular region] (R-HSA-381516)	0.556	3
UniProt:P05090 APOD	1	APOD [extracellular region] (R-HSA-5216199)	0.527	2
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.527	2
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.527	3
UniProt:Q96NW7 LRRC7	3	LRRC7 [extracellular region] (R-HSA-6799681) LRRC7 [specific granule lumen] (R-HSA-6799616) LRRC7 [cytosol] (R-HSA-9611351)	0.488	2

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