Reactome: A Curated Pathway Database

Influx of extracellular calcium

Stable Identifier
R-HSA-8863009
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Beta amyloid increases influx of extracellular calcium (Ca2+) through the plasma membrane, thus increasing the cytosolic Ca2+ concentration. The mechanism has not been completely elucidated (Lee et al. 2000, Abramov et al. 2004).

Literature References
Participants
Participant Of
This entity is regulated by:
Disease
Diseases
Name Identifier Synonyms
Alzheimer's disease 10652 AD, Alzheimers dementia, Alzheimer disease