Reactome | SPPL2A [plasma membrane]

SPPL2A [plasma membrane]

Stable Identifier

R-HSA-8863106

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

fullName evidence="13 15"Signal peptide peptidase-like 2A, SPP2A_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8TCT8 SPPL2A

Gene Names

SPPL2A, IMP3, PSL2, PSEC0147

Chain

signal peptide:1-25, chain:26-520

Reference Genes

BioGPS Gene:84888 SPPL2A

COSMIC (genes):SPPL2A SPPL2A

CTD Gene:84888 SPPL2A

dbSNP Gene:84888 SPPL2A

ENSEMBL:ENSG00000138600 SPPL2A

ENSEMBL_homo_sapiens_GENE:ENSG00000138600.11 SPPL2A

HGNC:30227 SPPL2A

KEGG Gene (Homo sapiens):84888 SPPL2A

Monarch:84888 SPPL2A

NCBI Gene:84888 SPPL2A

OMIM:608238 SPPL2A

UCSC:Q8TCT8 SPPL2A

Reference Transcript

RefSeq:NM_032802.3 SPPL2A

Other Identifiers

11721125_at

16809187

226353_PM_at

226353_at

227682_PM_at

227682_at

228478_PM_at

228478_at

3623481

3623483

3623487

3623488

3623864

3623866

3623867

3623868

3623869

3623870

3623871

3623872

3623878

3623880

3623882

3623886

3623892

3623893

3623897

3623898

3623900

3623903

3623906

3623907

3623908

3623909

3623910

3623911

44149_at

48405_at

60050_at

63296_at

7988753

84888

A_23_P77073

A_24_P646168

A_32_P50655

GE87776

GE88610

GO:0002376

GO:0003824

GO:0005515

GO:0005576

GO:0005615

GO:0005764

GO:0005765

GO:0005768

GO:0005770

GO:0005773

GO:0005783

GO:0005886

GO:0006508

GO:0006509

GO:0008233

GO:0010803

GO:0016020

GO:0016787

GO:0023052

GO:0030660

GO:0031293

GO:0031410

GO:0031902

GO:0033619

GO:0042500

GO:0042803

GO:0043226

GO:0043231

GO:0050776

GO:0070062

GO:0098553

GO:0098554

GO:0140096

HMNXSV003027538

HMNXSV003045881

Hs.167619.0.S1_3p_at

Hs.28980.0.A1_3p_at

Hs.99216.0.A1_3p_at

ILMN_1734229

PH_hs_0002526

TC15001358.hg

Participates

as a member of

SPPL2A,SPPL2B [plasma membrane] (Homo sapiens)

Inferred To

sppl2a [plasma membrane] (Xenopus tropicalis)

Sppl2a [plasma membrane] (Mus musculus)

Sppl2a [plasma membrane] (Rattus norvegicus)

SPPL2A [plasma membrane] (Bos taurus)

SPPL2A [plasma membrane] (Canis familiaris)

SPPL2A [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_116191.2

OpenTargets

ENSG00000138600

GeneCards

Q8TCT8

HPA

ENSG00000138600-SPPL2A

Ensembl

ENSG00000138600, ENSP00000261854, ENST00000261854

PRO

Q8TCT8

Pharos - Targets

Q8TCT8

Orphanet

24943

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3

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