Reactome | DCAF7 [nucleoplasm]

DCAF7 [nucleoplasm]

Stable Identifier

R-HSA-8863312

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DDB1- and CUL4-associated factor 7, DCAF7_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P61962 DCAF7

Gene Names

DCAF7, HAN11, WDR68

Chain

chain:1-342

Reference Genes

BioGPS Gene:10238 DCAF7

COSMIC (genes):DCAF7 DCAF7

CTD Gene:10238 DCAF7

dbSNP Gene:10238 DCAF7

ENSEMBL:ENSG00000136485 DCAF7

ENSEMBL_homo_sapiens_GENE:ENSG00000136485.16 DCAF7

HGNC:30915 DCAF7

KEGG Gene (Homo sapiens):10238 DCAF7

Monarch:10238 DCAF7

NCBI Gene:10238 DCAF7

OMIM:605973 DCAF7

UCSC:P61962 DCAF7

Reference Transcript

RefSeq:NM_005828.4 DCAF7

Other Identifiers

10238

11729624_at

11729625_a_at

11729626_a_at

11729627_at

11749947_a_at

11756112_x_at

16836965

209592_PM_s_at

209592_s_at

221744_3p_at

221744_PM_at

221744_at

221745_PM_at

221745_at

224730_PM_at

224730_at

224748_PM_at

224748_at

3730732

3730733

3730739

3730740

3730741

3730745

3730746

3730747

3730750

3730751

3730752

3730753

3730754

3730755

3730756

3730757

3730758

38171_at

41591_at

45796_at

48542_at

8009164

A_23_P26836

A_23_P422268

A_24_P91222

A_24_P916141

GE59587

GE86514

GE86647

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0016363

GO:0016567

GO:0016604

GO:0030674

GO:0032991

GO:0036211

GO:0043226

GO:0060090

GO:0080008

HMNXSV003011766

HMNXSV003043933

Hs.288283.0.S1_3p_at

Hs.288283.0.S2_3p_at

Hs.288283.0.S3_3p_x_at

Hs.50740.0.S1_3p_at

ILMN_1682264

ILMN_1706706

PH_hs_0024830

PH_hs_0033208

TC17000768.hg

U94747_at

g12654840_3p_a_at

Participates

as a member of

DCAF protein [nucleoplasm] (Homo sapiens)

Other forms of this molecule

Unfolded DCAF7 [cytosol]

Inferred To

wdr68 [nucleoplasm] (Dictyostelium discoideum)

swan-2 [nucleoplasm] (Caenorhabditis elegans)

wap [nucleoplasm] (Drosophila melanogaster)

Dcaf7 [nucleoplasm] (Mus musculus)

DCAF7 [nucleoplasm] (Bos taurus)

DCAF7 [nucleoplasm] (Canis familiaris)

DCAF7 [nucleoplasm] (Gallus gallus)

DCAF7 [nucleoplasm] (Rattus norvegicus)

DCAF7 [nucleoplasm] (Schizosaccharomyces pombe)

DCAF7 [nucleoplasm] (Sus scrofa)

dcaf7 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_005819.3

OpenTargets

ENSG00000136485

HPA

ENSG00000136485-DCAF7

GeneCards

P61962

Ensembl

ENST00000614556, ENSP00000403920, ENSP00000508930, ENST00000415273, ENSP00000509006, ENST00000690417, ENST00000431926, ENSP00000402312, ENST00000686337, ENSG00000136485, ENSP00000483236

PRO

P61962

Pharos - Targets

P61962

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13627 DYRK1A	1	DYRK1A [nucleoplasm] (R-HSA-1362267)	0.935	15
UniProt:Q9H2X6 HIPK2	3	p-HIPK2 [nucleoplasm] (R-HSA-6799375) HIPK2 [nucleoplasm] (R-HSA-3215222) monoSUMO1-K32-HIPK2 [nucleoplasm] (R-HSA-4090405)	0.729	11
UniProt:Q13233 MAP3K1	2	MAP3K1 [cytosol] (R-HSA-166866) p-T1400,T1412-MAP3K1 [cytosol] (R-HSA-2685607)	0.709	7
UniProt:P17987 TCP1	1	TCP1 [cytosol] (R-HSA-390448)	0.706	6
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	10
UniProt:P53350 PLK1	4	PLK1 [nucleoplasm] (R-HSA-156720) p-T210-PLK1 [cytosol] (R-HSA-3000318) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) PLK1 [cytosol] (R-HSA-164603)	0.638	3
UniProt:P55212 CASP6	5	CASP6 (1-293) [cytosol] (R-HSA-6798132) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128)	0.556	3
UniProt:P50548 ERF	3	p-T526-ERF [nucleoplasm] (R-HSA-3209166) p-T526-ERF [cytosol] (R-HSA-3209167) ERF [nucleoplasm] (R-HSA-2534321)	0.527	2
UniProt:Q9H0D6 XRN2	2	XRN2 [nucleoplasm] (R-HSA-6791205) XRN2 [cytosol] (R-HSA-391297)	0.508	2
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.508	2
UniProt:Q8NBS9 TXNDC5	4	TXNDC5 [Golgi lumen] (R-HSA-434325) TXNDC5 [lysosomal lumen] (R-HSA-429813) TXNDC5 [extracellular region] (R-HSA-6806246) TXNDC5 [azurophil granule lumen] (R-HSA-6799367)	0.508	2
UniProt:P41743 PRKCI	3	PRKCI [nucleoplasm] (R-HSA-9021345) PRKCI [cytosol] (R-HSA-58206) PRKCI [plasma membrane] (R-HSA-420005)	0.508	2
UniProt:Q9UBC2 EPS15L1	2	EPS15L1 [plasma membrane] (R-HSA-182937) EPS15L1 [cytosol] (R-HSA-8935900)	0.508	2
UniProt:P49757 NUMB	1	NUMB [plasma membrane] (R-HSA-443595)	0.508	2
UniProt:P63208 SKP1	2	SKP1 [nucleoplasm] (R-HSA-187538) SKP1 [cytosol] (R-HSA-174150)	0.508	2
UniProt:Q9C0C7 AMBRA1	2	p-AMBRA1 [cytosol] (R-HSA-1632854) AMBRA1 [cytosol] (R-HSA-1632831)	0.508	2
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.508	3