AGFG1 binds VAMP7

Stable Identifier
R-HSA-8863718
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

AGFG1, also known as HRB (HIV-1 Rev-binding), is a clathrin adaptor and ArfGAP that interacts with the R-SNARE VAMP7 to mediate its endocytosis from the plasma membrane (Pryor et al, 2008; Chaineau et al, 2008). AGFG1 also interacts with a number of other endocytic proteins such as EPS15, EPS15R, FCHos and ITSNs (Doria et al, 1999; Salcini et al, 1997; Schmid et al, 2006; Umasankar et al, 2012).

Participants
Participant Of
Orthologous Events