Reactome | TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-HSA-8863953

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

Antigen peptide transporter 1, TAP1_HUMAN

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External Reference Information

External Reference

UniProt:Q03518 TAP1

Gene Names

TAP1, ABCB2, PSF1, RING4, Y3

Chain

chain:1-808

Reference Genes

BioGPS Gene:6890 TAP1

COSMIC (genes):TAP1 TAP1

CTD Gene:6890 TAP1

dbSNP Gene:6890 TAP1

ENSEMBL:ENSG00000168394 TAP1

ENSEMBL:ENSG00000206297 TAP1

ENSEMBL:ENSG00000224212 TAP1

ENSEMBL:ENSG00000226173 TAP1

ENSEMBL:ENSG00000227816 TAP1

ENSEMBL:ENSG00000230705 TAP1

ENSEMBL:ENSG00000232367 TAP1

HGNC:43 TAP1

KEGG Gene (Homo sapiens):6890 TAP1

Monarch:6890 TAP1

NCBI Gene:6890 TAP1

OMIM:170260 TAP1

UCSC:Q03518 TAP1

Reference Transcript

Other Identifiers

0003120279

11730729_a_at

11757351_a_at

17017979

17027144

17029788

17032476

17034791

17037271

17039977

17042487

1JJ7

202307_s_at

2950215

2950216

2950217

2950219

2950221

2950222

2950223

2950224

2950226

2950228

2950230

2950231

2950232

2950233

2950234

2950235

2950236

2950237

40153_at

5U1D

6890

72354

8125512

8178867

8180061

9516

A0A0S2Z4R8

A0A0S2Z5A6

A0A140T9T7

A_23_P59005

AAC12902

AAC12903

AAC12904

AAC12905

AAC12906

AAD14056

AAH14081

AL669918

AL671681

AL935043

ALQ33804

ARB08462

ARB08463

ARB08464

ARB08465

ARB08473

ARB08474

ARB08477

ARB08481

ARB08482

ARB08484

BC014081

BX927138

CAA40740

CAA40741

CAA47025

CAA60785

CAB009516

CCDS4758

CH471081

CR753889

CR762476

CR933844

EAX03647

ENSG00000168394

ENSG00000206297

ENSG00000224212

ENSG00000226173

ENSG00000227816

ENSG00000230705

ENSG00000232367

ENSP00000346206

ENSP00000372722

ENSP00000401149

ENSP00000402316

ENSP00000405356

ENSP00000413080

ENSP00000415660

ENST00000354258

ENST00000354258.4

ENST00000383235

ENST00000414467

ENST00000418205

ENST00000424897

ENST00000439781

ENST00000440894

EntrezGene:6890

EntrezGene:TAP1

g9665247_3p_a_at

GE79181

GO:0000166

GO:0002250

GO:0002376

GO:0002474

GO:0002479

GO:0003674

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005783

GO:0005789

GO:0005815

GO:0005856

GO:0006810

GO:0006950

GO:0006952

GO:0008150

GO:0015031

GO:0015433

GO:0015440

GO:0015833

GO:0016020

GO:0016021

GO:0016032

GO:0016192

GO:0016887

GO:0019885

GO:0022857

GO:0023029

GO:0030176

GO:0030670

GO:0031410

GO:0032991

GO:0033116

GO:0042287

GO:0042288

GO:0042605

GO:0042626

GO:0042803

GO:0042824

GO:0042825

GO:0043167

GO:0043226

GO:0043531

GO:0044403

GO:0046967

GO:0046978

GO:0046979

GO:0055085

GO:0061024

GO:0099131

GO:1904680

GO:1990668

HGNC:43

HPA072354

ILMN_1751079

IPR003439

IPR003593

IPR011527

IPR013305

IPR013306

IPR017871

IPR027417

IPR036640

IPR039421

KU178346

KY497372

KY497373

KY497374

KY497375

KY497383

KY497384

KY497387

KY497391

KY497392

KY497394

L21204

L21205

L21206

L21207

L21208

MIM:170260

MIM:604571

NM_000593

NM_001292022

NP_000584

NP_001278951

PF00005

PF00664

PH_hs_0032801

PR01896

S70274

SM00382

TAP1

TAP1-201

TAP1-207

TAP1-210

TAP1-216

TAP1-219

TAP1-222

TAP1-225

TC06001574.hg

TC6_apd_hap1000105.hg

TC6_cox_hap2000199.hg

TC6_dbb_hap3000185.hg

TC6_mann_hap4000167.hg

TC6_mcf_hap5000174.hg

TC6_qbl_hap6000187.hg

TC6_ssto_hap7000169.hg

UPI000002D4E6

X57521

X57522

X57522_at

X66401

X87344

Participant Of

hasComponent

TAP [endoplasmic reticulum-Golgi intermediate compartment membrane]

Other forms of this molecule

TAP1 [phagocytic vesicle membrane]

TAP1 [endoplasmic reticulum membrane]

Inferred To

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Gallus gallus)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)

TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Xenopus tropicalis)

Homologues of TAP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001278951.1, NP_000584.2

OpenTargets

ENSG00000168394

GeneCards

Q03518

PRO

Q03518

Orphanet

16436

HMDB Protein

HMDBP10764

PDB

5U1D, 1JJ7

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15533 TAPBP	3	TAPBP [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863976) TAPBP [phagocytic vesicle membrane] (R-HSA-1236750) TAPBP [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-983083)	0.803	14
UniProt:P30101 PDIA3	3	PDIA3 [recycling endosome membrane] (R-HSA-8863849) PDIA3 [phagocytic vesicle] (R-HSA-1236870) PDIA3 [endoplasmic reticulum lumen] (R-HSA-901028)	0.623	5
UniProt:P61769 B2M	11	B2M(21-119) [early endosome lumen] (R-HSA-1236827) B2M(21-119) [early endosome membrane] (R-HSA-182298) B2M(21-119) [phagocytic vesicle membrane] (R-HSA-1236891) B2M(21-119) [recycling endosome membrane] (R-HSA-8863880) B2M(21-119) [Golgi membrane] (R-HSA-983403) B2M(21-119) [ER to Golgi transport vesicle membrane] (R-HSA-983378) B2M(21-119) [endoplasmic reticulum lumen] (R-HSA-983063) B2M(21-119) [tertiary granule lumen] (R-HSA-6800179) B2M(21-119) [extracellular region] (R-HSA-1302721) B2M(21-119) [specific granule lumen] (R-HSA-6806144) B2M(21-119) [plasma membrane] (R-HSA-167743)	0.527	3
UniProt:P27797 CALR	6	CALR [extracellular region] (R-HSA-2197641) CALR [endocytic vesicle lumen] (R-HSA-2239448) CALR [endoplasmic reticulum lumen] (R-HSA-195905) CALR [phagocytic vesicle membrane] (R-HSA-1236879) CALR [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-8863866) CALR [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-985502)	0.499	2
UniProt:P07237 P4HB	3	p-P4HB [endoplasmic reticulum lumen] (R-HSA-8956902) P4HB [endoplasmic reticulum lumen] (R-HSA-174692) HC53,56-P4HB [endoplasmic reticulum lumen] (R-HSA-3341287)	0.499	4
UniProt:Q14973 SLC10A1	1	SLC10A1 [plasma membrane] (R-HSA-194116)	0.488	2
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.488	2