Reactome | CITED1 [nucleoplasm]

CITED1 [nucleoplasm]

Stable Identifier

R-HSA-8864301

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Cbp/p300-interacting transactivator 1, CITE1_HUMAN, MSG1, Melanocyte-specific protein 1

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Homo sapiens)
      - Activation of the TFAP2 (AP-2) family of transcription factors (Homo sapiens)
        
        TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Homo sapiens)
        
        CITED2,CITED4,(CITED1) [nucleoplasm] (Homo sapiens)
        
        CITED1 [nucleoplasm] (Homo sapiens)
        
        TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP [nucleoplasm] (Homo sapiens)
        
        CITED2,CITED4,(CITED1) [nucleoplasm] (Homo sapiens)
        
        CITED1 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q99966 CITED1

Gene Names

CITED1, MSG1

Chain

chain:1-193

Reference Genes

BioGPS Gene:4435 CITED1

COSMIC (genes):CITED1 CITED1

CTD Gene:4435 CITED1

dbSNP Gene:4435 CITED1

ENSEMBL:ENSG00000125931 CITED1

HGNC:1986 CITED1

KEGG Gene (Homo sapiens):4435 CITED1

Monarch:4435 CITED1

NCBI Gene:4435 CITED1

OMIM:300149 CITED1

UCSC:Q99966 CITED1

Reference Transcript

Other Identifiers

0001940609

11732702_a_at

17112020

207144_s_at

35976_at

36615_at

4012179

4012180

4012181

4012182

4012183

4012185

4012186

4012191

4012194

4012195

4012196

4012197

4012198

4435

49051

8173524

A_23_P73526

AAC51113

AAH04240

AB451286

AB451418

AL135749

BAG70100

BAG70232

BC004240

C9J1P6

C9J300

C9J7P8

C9JRD8

CCDS14419

CCDS48136

CH471213

CITED1

CITED1-201

CITED1-202

CITED1-206

CITED1-207

CITED1-209

CITED1-211

EAW71819

ENSG00000125931

ENSP00000246139

ENSP00000362721

ENSP00000388548

ENSP00000401764

ENSP00000403274

ENSP00000499148

ENST00000246139

ENST00000246139.9

ENST00000373619

ENST00000373619.7

ENST00000431381

ENST00000431381.5

ENST00000445983

ENST00000445983.5

ENST00000453707

ENST00000453707.6

ENST00000651998

EntrezGene:4435

EntrezGene:CITED1

g4758735_3p_a_at

GE59316

GO:0000003

GO:0000578

GO:0001570

GO:0001656

GO:0001658

GO:0001890

GO:0002376

GO:0003340

GO:0003674

GO:0003677

GO:0003682

GO:0003700

GO:0003713

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006355

GO:0006357

GO:0006810

GO:0006913

GO:0006915

GO:0006950

GO:0007165

GO:0007179

GO:0007267

GO:0007275

GO:0007420

GO:0008022

GO:0008150

GO:0008219

GO:0008283

GO:0009058

GO:0009790

GO:0010628

GO:0019748

GO:0030154

GO:0030178

GO:0030318

GO:0030511

GO:0032496

GO:0032868

GO:0034097

GO:0034341

GO:0034641

GO:0042438

GO:0042803

GO:0042981

GO:0043226

GO:0043473

GO:0043524

GO:0043627

GO:0044212

GO:0045668

GO:0045892

GO:0045893

GO:0048856

GO:0050693

GO:0051591

GO:0060231

GO:0060395

GO:0060711

GO:0060712

GO:0070410

GO:0070555

GO:0070669

GO:0070670

GO:0070741

GO:0071104

GO:0071105

GO:0071107

GO:0071559

GO:1902462

HGNC:1986

HPA049051

ILMN_1691641

IPR007576

MIM:300149

N30508

NM_001144885

NM_001144886

NM_001144887

NM_004143

NP_001138357

NP_001138358

NP_001138359

NP_004134

PF04487

TC0X001140.hg

U65092

U65092_at

UPI000013CBD9

UPI0000212358

XM_011530958

XP_011529260

Participant Of

hasMember

histone acetyltransferases [nucleoplasm]

hasComponent

CITED1:EP300:ESR1:estrogen:TGFA gene promoter [nucleoplasm]

input

CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter

hasCandidate

CITED2,CITED4,(CITED1) [nucleoplasm]

Inferred To

CITED1 [nucleoplasm] (Bos taurus)

CITED1 [nucleoplasm] (Canis familiaris)

CITED1 [nucleoplasm] (Sus scrofa)

Cited1 [nucleoplasm] (Mus musculus)

Cited1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_004134.2, NP_001138359.1, NP_001138358.1, XP_011529260.1, NP_001138357.1

OpenTargets

ENSG00000125931

GeneCards

Q99966

HPA

ENSG00000125931-CITED1

Ensembl

ENSP00000388548, ENSP00000246139, ENST00000651998, ENST00000431381, ENST00000246139, ENST00000453707, ENSP00000362721, ENSG00000125931, ENST00000445983, ENST00000373619, ENSP00000403274, ENSP00000499148, ENSP00000401764

PRO

Q99966

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05412 JUN	4	p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [nucleoplasm] (R-HSA-450250) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.524	2
UniProt:P03372 ESR1	8	SUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.524	3

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