Reactome | CITED1 [nucleoplasm]

CITED1 [nucleoplasm]

Stable Identifier

R-HSA-8864301

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Cbp/p300-interacting transactivator 1, CITE1_HUMAN, MSG1, Melanocyte-specific protein 1

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Homo sapiens)
      - Activation of the TFAP2 (AP-2) family of transcription factors (Homo sapiens)
        
        TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Homo sapiens)
        
        CITED2,CITED4,(CITED1) [nucleoplasm] (Homo sapiens)
        
        CITED1 [nucleoplasm] (Homo sapiens)
        
        TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP [nucleoplasm] (Homo sapiens)
        
        CITED2,CITED4,(CITED1) [nucleoplasm] (Homo sapiens)
        
        CITED1 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q99966 CITED1

Gene Names

CITED1, MSG1

Chain

chain:1-193

Reference Genes

BioGPS Gene:4435 CITED1

COSMIC (genes):CITED1 CITED1

CTD Gene:4435 CITED1

dbSNP Gene:4435 CITED1

ENSEMBL:ENSG00000125931 CITED1

HGNC:1986 CITED1

KEGG Gene (Homo sapiens):4435 CITED1

Monarch:4435 CITED1

NCBI Gene:4435 CITED1

OMIM:300149 CITED1

UCSC:Q99966 CITED1

Reference Transcript

Other Identifiers

0001940609

11732702_a_at

17112020

207144_s_at

35976_at

36615_at

4012179

4012180

4012181

4012182

4012183

4012185

4012186

4012191

4012194

4012195

4012196

4012197

4012198

4435

8173524

A_23_P73526

GE59316

GO:0000003

GO:0000578

GO:0001570

GO:0001656

GO:0001658

GO:0001890

GO:0002376

GO:0003340

GO:0003674

GO:0003682

GO:0003713

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006355

GO:0006357

GO:0006810

GO:0006913

GO:0006915

GO:0006950

GO:0007165

GO:0007179

GO:0007267

GO:0007275

GO:0007420

GO:0008022

GO:0008150

GO:0008219

GO:0008283

GO:0009058

GO:0009790

GO:0010628

GO:0019748

GO:0030154

GO:0030178

GO:0030318

GO:0030511

GO:0032496

GO:0032868

GO:0034097

GO:0034341

GO:0034641

GO:0042438

GO:0042803

GO:0042981

GO:0043226

GO:0043473

GO:0043524

GO:0043627

GO:0045668

GO:0045892

GO:0045893

GO:0045944

GO:0048856

GO:0050693

GO:0051591

GO:0060231

GO:0060395

GO:0060711

GO:0060712

GO:0070410

GO:0070555

GO:0070669

GO:0070670

GO:0070741

GO:0071104

GO:0071105

GO:0071107

GO:0071559

GO:1902462

HMNXSV003054135

ILMN_1691641

TC0X001140.hg

U65092_at

g4758735_3p_a_at

Participates

as a member of

histone acetyltransferases [nucleoplasm] (Homo sapiens)

as a component of

CITED1:EP300:ESR1:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)

as an input of

CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Homo sapiens)

as a candidate of

CITED2,CITED4,(CITED1) [nucleoplasm] (Homo sapiens)

Inferred To

cited1 [nucleoplasm] (Danio rerio)

CITED1 [nucleoplasm] (Canis familiaris)

CITED1 [nucleoplasm] (Sus scrofa)

CITED1 [nucleoplasm] (Xenopus tropicalis)

Cited1 [nucleoplasm] (Mus musculus)

Cited1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

XP_011529260.1, NP_001138358.1, NP_004134.2, NP_001138359.1, NP_001138357.1

OpenTargets

ENSG00000125931

GeneCards

Q99966

HPA

ENSG00000125931-CITED1

Ensembl

ENSP00000499148, ENST00000445983, ENSP00000403274, ENSP00000401764, ENSP00000246139, ENSG00000125931, ENST00000453707, ENST00000246139, ENST00000431381, ENSP00000388548, ENST00000651998, ENSP00000362721, ENST00000373619

PRO

Q99966

Pharos - Targets

Q99966

HMDB Protein

HMDBP14522

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13473-2 P134732			0.556	3
UniProt:P55212 CASP6	5	CASP6 (1-293) [cytosol] (R-HSA-6798132) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128)	0.556	3
UniProt:P06307 CCK	1	CCK [extracellular region] (R-HSA-388539)	0.556	3
UniProt:Q0VDC6 Q0VDC6			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:P03372 ESR1	8	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.524	3
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.524	2