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CITED1 [nucleoplasm]
Stable Identifier
R-HSA-8864301
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Cbp/p300-interacting transactivator 1, CITE1_HUMAN, MSG1, Melanocyte-specific protein 1
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Homo sapiens)
Activation of the TFAP2 (AP-2) family of transcription factors (Homo sapiens)
TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Homo sapiens)
CITED2,CITED4,(CITED1) [nucleoplasm] (Homo sapiens)
CITED1 [nucleoplasm] (Homo sapiens)
TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP [nucleoplasm] (Homo sapiens)
CITED2,CITED4,(CITED1) [nucleoplasm] (Homo sapiens)
CITED1 [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Estrogen-dependent gene expression (Homo sapiens)
CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Homo sapiens)
CITED1 [nucleoplasm] (Homo sapiens)
CITED1:EP300:ESR1:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
CITED1 [nucleoplasm] (Homo sapiens)
Estrogen-responsive TFF1 gene expression (Homo sapiens)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Homo sapiens)
histone acetyltransferases [nucleoplasm] (Homo sapiens)
CITED1 [nucleoplasm] (Homo sapiens)
Histone acetyltransferases are recruited to the TFF1 gene (Homo sapiens)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Homo sapiens)
histone acetyltransferases [nucleoplasm] (Homo sapiens)
CITED1 [nucleoplasm] (Homo sapiens)
histone acetyltransferases [nucleoplasm] (Homo sapiens)
CITED1 [nucleoplasm] (Homo sapiens)
TGFA gene expression is stimulated by the CITED1:EP300:ESR1:estrogen (Homo sapiens)
CITED1:EP300:ESR1:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
CITED1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99966 CITED1
Gene Names
CITED1, MSG1
Chain
chain:1-193
Reference Genes
BioGPS Gene:4435 CITED1
COSMIC (genes):CITED1 CITED1
CTD Gene:4435 CITED1
dbSNP Gene:4435 CITED1
ENSEMBL:ENSG00000125931 CITED1
HGNC:1986 CITED1
KEGG:hsa:4435 CITED1
Monarch:4435 CITED1
NCBI Gene:4435 CITED1
OMIM:300149 CITED1
UCSC:Q99966 CITED1
Reference Transcript
RefSeq:XM_011530958.1 CITED1
RefSeq:NM_001144887.1 CITED1
RefSeq:NM_004143.3 CITED1
RefSeq:NM_001144886.1 CITED1
RefSeq:NM_001144885.1 CITED1
Other Identifiers
11732702_a_at
17112020
207144_PM_s_at
207144_s_at
35976_at
36615_at
4012179
4012180
4012181
4012182
4012183
4012185
4012186
4012187
4012191
4012192
4012193
4012194
4012195
4012196
4012197
4012198
4435
8173524
A_23_P73526
GE59316
GO:0001570
GO:0001656
GO:0001658
GO:0001890
GO:0003682
GO:0003713
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006355
GO:0006357
GO:0006913
GO:0006915
GO:0007179
GO:0007420
GO:0010628
GO:0012501
GO:0030154
GO:0030178
GO:0030318
GO:0030511
GO:0032496
GO:0032868
GO:0034097
GO:0034341
GO:0042438
GO:0042803
GO:0042981
GO:0043226
GO:0043473
GO:0043524
GO:0043627
GO:0045668
GO:0045892
GO:0045893
GO:0045944
GO:0048856
GO:0050693
GO:0051591
GO:0060090
GO:0060231
GO:0060395
GO:0060711
GO:0060712
GO:0070410
GO:0070555
GO:0070669
GO:0070670
GO:0070741
GO:0071104
GO:0071105
GO:0071107
GO:0071559
GO:0140110
GO:1902462
HMNXSV003054135
ILMN_1691641
TC0X001140.hg
U65092_at
g4758735_3p_a_at
Participates
as a member of
histone acetyltransferases [nucleoplasm] (Homo sapiens)
as a component of
CITED1:EP300:ESR1:estrogen:TGFA gene promoter [nucleoplasm] (Homo sapiens)
as an input of
CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Homo sapiens)
as a candidate of
CITED2,CITED4,(CITED1) [nucleoplasm] (Homo sapiens)
Inferred To
cited1 [nucleoplasm]
(Danio rerio)
CITED1 [nucleoplasm]
(Bos taurus)
CITED1 [nucleoplasm]
(Canis familiaris)
CITED1 [nucleoplasm]
(Sus scrofa)
Cited1 [nucleoplasm]
(Mus musculus)
Cited1 [nucleoplasm]
(Rattus norvegicus)
Cross References
ENSEMBL
ENSP00000401764
,
ENSP00000246139
,
ENST00000453707
,
ENST00000651998
,
ENST00000445983
,
ENSP00000499148
,
ENST00000431381
,
ENST00000246139
,
ENSP00000388548
,
ENST00000373619
,
ENSP00000362721
,
ENSP00000403274
OpenTargets
ENSG00000125931
HPA
ENSG00000125931-CITED1
PRO
Q99966
Pharos - Targets
Q99966
HMDB Protein
HMDBP14522
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P55212 CASP6
5
CASP6(194-293) [cytosol]
(R-HSA-266128)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
0.556
3
UniProt:P13473-2 P134732
0.556
3
IntAct:EBI-25847655 CCSB
0.556
3
UniProt:Q0VDC6 Q0VDC6
0.556
3
UniProt:P06307 CCK
1
CCK [extracellular region]
(R-HSA-388539)
0.556
3
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.524
3
UniProt:P05412 JUN
4
JUN [nucleoplasm]
(R-HSA-450250)
p-S63,S73-JUN [nucleoplasm]
(R-HSA-450237)
JUN [cytosol]
(R-HSA-168194)
p-S63,S73-JUN [cytosol]
(R-HSA-8868682)
0.524
2
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