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TFAP2A homodimer:VEGFA Gene [nucleoplasm]
Stable Identifier
R-HSA-8864742
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Homo sapiens)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors (Homo sapiens)
TFAP2A homodimer binds the VEGFA gene promoter (Homo sapiens)
TFAP2A homodimer:VEGFA Gene [nucleoplasm] (Homo sapiens)
VEGFA gene expression is inhibited by the TFAP2A homodimer (Homo sapiens)
TFAP2A homodimer:VEGFA Gene [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
14744778
Activator protein 2alpha inhibits tumorigenicity and represses vascular endothelial growth factor transcription in prostate cancer cells
Bar-Eli, M
,
Song, R
,
Ruiz, M
,
Pettaway, C
,
Stoeltzing, O
,
Ellis, L
Cancer Res.
2004
Participants
components
TFAP2A homodimer [nucleoplasm]
(Homo sapiens)
VEGFA gene [nucleoplasm]
(Homo sapiens)
Participates
as an output of
TFAP2A homodimer binds the VEGFA gene promoter (Homo sapiens)
This entity regulates
Negatively
VEGFA gene expression is inhibited by the TFAP2A homodimer
(Homo sapiens)
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