TGFA gene expression is stimulated by the TFAP2A homodimer

Stable Identifier
R-HSA-8864999
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The TGFA gene encodes the precursor of the transforming growth factor alpha (TGF alpha). Binding of the TFAP2A homodimer to the promoter of the TGFA gene stimulates TGFA transcription (Wang et al. 1997).

Literature References
PubMed ID Title Journal Year
9162057 Transcription factor AP-2 controls transcription of the human transforming growth factor-alpha gene

Wang, D, Shin, TH, Kudlow, JE

J. Biol. Chem. 1997
Participants
Participant Of
This event is regulated
Authored
Reviewed
Created