KMT2A (MLL) binds RUNX1

Stable Identifier
R-HSA-8865482
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Histone methyltransferase KMT2A (MLL) binds to RUNX1 (AML1) both in the presence and absence of CBFB (Huang et al. 2011).

Literature References
PubMed ID Title Journal Year
22012064 The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

Huang, G, Zhao, X, Wang, L, Elf, S, Xu, H, Zhao, X, Sashida, G, Zhang, Y, Liu, Y, Lee, J, Menendez, S, Yang, Y, Yan, X, Zhang, P, Tenen, DG, Osato, M, Hsieh, JJ, Nimer, SD

Blood 2011
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created