FOXP3 gene expression is stimulated by RUNX1:CBFB

Stable Identifier
R-HSA-8865546
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Binding of the RUNX1:CBFB complex to the promoter of the FOXP3 gene stimulates FOXP3 transcription (Kitoh et al. 2009).

Literature References
PubMed ID Title Journal Year
19800266 Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells

Kitoh, A, Ono, M, Naoe, Y, Ohkura, N, Yamaguchi, T, Yaguchi, H, Kitabayashi, I, Tsukada, T, Nomura, T, Miyachi, Y, Taniuchi, I, Sakaguchi, S

Immunity 2009
Participants
Participant Of
This event is regulated
Authored
Reviewed
Created