ZRSR2 [nucleoplasm]

Stable Identifier
R-HSA-8865914
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2, U2AFM_HUMAN
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
25586593 Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome

Madan, V, Kanojia, D, Li, J, Okamoto, R, Sato-Otsubo, A, Kohlmann, A, Sanada, M, Grossmann, V, Sundaresan, J, Shiraishi, Y, Miyano, S, Thol, F, Ganser, A, Yang, H, Haferlach, T, Ogawa, S, Koeffler, HP

Nat Commun 2015
21041408 The U2AF35-related protein Urp contacts the 3' splice site to promote U12-type intron splicing and the second step of U2-type intron splicing

Shen, H, Zheng, X, Luecke, S, Green, MR

Genes Dev. 2010
External Reference Information
External Reference
UniProt:Q15696 ZRSR2
Gene Names
ZRSR2, U2AF1-RS2, U2AF1L2, U2AF1RS2, URP
Chain
chain:1-482
Reference Genes
BioGPS Gene:8233 ZRSR2
COSMIC (genes):ZRSR2 ZRSR2
CTD Gene:8233 ZRSR2
dbSNP Gene:8233 ZRSR2
ENSEMBL:ENSG00000169249 ZRSR2
HGNC:23019 ZRSR2
KEGG Gene (Homo sapiens):8233 ZRSR2
Monarch:8233 ZRSR2
NCBI Gene:8233 ZRSR2
OMIM:300028 ZRSR2
UCSC:Q15696 ZRSR2
Reference Transcript
Other Identifiers
0001410347
11758542_x_at
208174_3p_x_at
208174_x_at
213876_3p_x_at
213876_x_at
2824319
2824320
2824321
2824322
2824324
35060_at
38523_f_at
3969948
3969950
3969953
3969956
3969957
3969960
3969963
3969968
3969969
3969970
3969971
3969973
3969974
3969975
3969976
8166195
8233
A_23_P85053
D49677_at
GE57231
GO:0000245
GO:0000398
GO:0003674
GO:0003676
GO:0003723
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005681
GO:0005689
GO:0006397
GO:0008150
GO:0008380
GO:0022607
GO:0022618
GO:0030628
GO:0032991
GO:0034641
GO:0042802
GO:0043167
GO:0043226
GO:0046872
GO:0065003
GO:0089701
Hs.171909.1.S1_3p_a_at
ILMN_1773868
ILMN_1797537
ILMN_3247732
TC0X000072.hg
g13186299_3p_s_at
g4827045_3p_a_at
Participant Of
hasComponent
input
Inferred To
Dmel\CG3294 [nucleoplasm] (Drosophila melanogaster)
ZRSR2 [nucleoplasm] (Canis familiaris)
ZRSR2 [nucleoplasm] (Gallus gallus)
ZRSR2 [nucleoplasm] (Sus scrofa)
ZRSR2 [nucleoplasm] (Xenopus tropicalis)
zrsr2 [nucleoplasm] (Danio rerio)
Ghost homologue of ZRSR2 [nucleoplasm] (Caenorhabditis elegans)
Ghost homologue of ZRSR2 [nucleoplasm] (Dictyostelium discoideum)
Zrsr2 [nucleoplasm] (Mus musculus)
Zrsr2 [nucleoplasm] (Rattus norvegicus)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Orphanet
Interactors (16)
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