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SH3BP4 [cytosol]
Stable Identifier
R-HSA-8866227
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SH3 domain-binding protein 4, SH3B4_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P02786
Expand all
Cellular responses to external stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to starvation (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
RRAGA,B exchanges GDP for GTP (Homo sapiens)
SH3BP4 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9P0V3 SH3BP4
Gene Names
SH3BP4, BOG25, EHB10, TTP
Chain
chain:1-963
Reference Genes
BioGPS Gene:23677 SH3BP4
COSMIC (genes):SH3BP4 SH3BP4
CTD Gene:23677 SH3BP4
dbSNP Gene:23677 SH3BP4
ENSEMBL:ENSG00000130147 SH3BP4
HGNC:10826 SH3BP4
KEGG Gene (Homo sapiens):23677 SH3BP4
Monarch:23677 SH3BP4
NCBI Gene:23677 SH3BP4
OMIM:605611 SH3BP4
UCSC:Q9P0V3 SH3BP4
Reference Transcript
RefSeq:XM_011510892.1 SH3BP4
RefSeq:XM_011510891.2 SH3BP4
RefSeq:NM_014521.2 SH3BP4
RefSeq:XM_011510893.1 SH3BP4
RefSeq:XM_011510894.2 SH3BP4
Other Identifiers
0006660497
11720658_a_at
11751004_x_at
11754466_a_at
16892750
222258_s_at
23677
2533492
2533494
2533511
2533512
2533513
2533525
2533538
2533539
2533540
2533543
2533544
2533545
2533546
2533547
2533548
2533555
2533556
2533557
2533558
2533559
2533561
63396_at
8049435
A_14_P120051
A_23_P79259
A_33_P3273369
GE58598
GO:0003674
GO:0005092
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005886
GO:0005905
GO:0006810
GO:0006897
GO:0006914
GO:0007165
GO:0008150
GO:0008283
GO:0008285
GO:0009056
GO:0010508
GO:0016020
GO:0016192
GO:0017016
GO:0019899
GO:0030136
GO:0030234
GO:0030308
GO:0031267
GO:0031410
GO:0032007
GO:0034260
GO:0040007
GO:0042802
GO:0043226
GO:0050790
GO:0061462
GO:0070062
GO:0071230
HMNXSV003011512
Hs.17667.1.S1_3p_a_at
ILMN_1785330
PH_hs_0027587
PH_hs_0030751
TC02001426.hg
This entity regulates
Negatively
RRAGA,B exchanges GDP for GTP
(Homo sapiens)
Inferred To
sh3bp4a [cytosol]
(Danio rerio)
SH3BP4 [cytosol]
(Bos taurus)
SH3BP4 [cytosol]
(Canis familiaris)
SH3BP4 [cytosol]
(Gallus gallus)
SH3BP4 [cytosol]
(Sus scrofa)
Sh3bp4 [cytosol]
(Mus musculus)
Sh3bp4 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_055336.1
,
XP_011509194.1
,
XP_011509196.1
,
XP_011509193.1
,
XP_011509195.1
OpenTargets
ENSG00000130147
HPA
ENSG00000130147-SH3BP4
GeneCards
Q9P0V3
Ensembl
ENST00000409212
,
ENST00000344528
,
ENST00000392011
,
ENSP00000386862
,
ENSP00000340237
,
ENSP00000375867
,
ENSG00000130147
PRO
Q9P0V3
Orphanet
26463
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P61981 YWHAG
1
YWHAG [cytosol]
(R-HSA-380312)
0.763
5
UniProt:P02786 TFRC
5
TFRC(1-760) [Golgi membrane]
(R-HSA-434330)
TFRC(1-760) [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869124)
TFRC(1-760) [cytoplasmic vesicle membrane]
(R-HSA-434196)
TFRC(1-760) [plasma membrane]
(R-HSA-917983)
TFRC(1-760) [endosome membrane]
(R-HSA-8961829)
0.668
6
UniProt:P39052 Dnm2
5
Dnm2 [lysosomal membrane]
(R-RNO-2980840)
Dnm2 [Golgi membrane]
(R-RNO-2980842)
Dnm2 [endocytic vesicle membrane]
(R-RNO-2029000)
Dynamin-2 [plasma membrane]
(R-RNO-941852)
Dnm2 [cytosol]
(R-RNO-9619847)
0.611
5
UniProt:P27348 YWHAQ
1
YWHAQ [cytosol]
(R-HSA-1445116)
0.564
2
UniProt:P50570 DNM2
5
DNM2 [cytosol]
(R-HSA-2213180)
DNM2 [Golgi membrane]
(R-HSA-2980842)
DNM2 [plasma membrane]
(R-HSA-2984201)
DNM2 [endocytic vesicle membrane]
(R-HSA-2029000)
DNM2 [lysosomal membrane]
(R-HSA-2980840)
0.524
3
UniProt:Q9HB21 PLEKHA1
1
PLEKHA1 [plasma membrane]
(R-HSA-8870328)
0.508
2
UniProt:Q9ULV3 CIZ1
0.508
2
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