Reactome: A Curated Pathway Database

ADBRK1,2 phosphorylate AVPR2

Stable Identifier
R-HSA-8866268
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

AVPR2 is phosphorylated by ADBRK1 and 2 in an agonist-dependent manner as a prerequisite for beta-arrestin binding and endocytosis (Ren et al, 2005; reviewed in Gurevich and Gurevich, 2006).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
beta-adrenergic receptor kinase activity of ADBRK1,2 [cytosol] ADBRK1,2 [cytosol] beta-adrenergic receptor kinase activity (0047696)
Orthologous Events