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ADBRK1,2 phosphorylate AVPR2

Stable Identifier
R-HSA-8866268
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

AVPR2 is phosphorylated by ADBRK1 and 2 in an agonist-dependent manner as a prerequisite for beta-arrestin binding and endocytosis (Ren et al, 2005; reviewed in Gurevich and Gurevich, 2006).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
beta-adrenergic receptor kinase activity of ADBRK1,2 [cytosol]
Physical Entity
Activity
Orthologous Events