pre-VLDL binds lipids to form VLDL

Stable Identifier
R-HSA-8866304
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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pre-VLDL binds lipids to form VLDL
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The assembly of very low-density lipoprotein (VLDL) occurs in two steps (Olofsson et al. 2000). In the second step, pre-VLDL in the smooth ER lumen binds the major lipids that form bona fide VLDL; triacylglycerols (TAG) (50%), phospholipids (PL) (20%), cholesterol (CHOL) (10%) and cholesteryl esters (CHEST) (5%).
Literature References
PubMed ID Title Journal Year
11369260 Intracellular assembly of VLDL: two major steps in separate cell compartments

Asp, L, Olofsson, SO, Stillemark-Billton, P

Trends Cardiovasc. Med. 2000
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Orthologous Events
pre-VLDL binds lipids to form VLDL (Bos taurus)
pre-VLDL binds lipids to form VLDL (Canis familiaris)
pre-VLDL binds lipids to form VLDL (Gallus gallus)
pre-VLDL binds lipids to form VLDL (Mus musculus)
pre-VLDL binds lipids to form VLDL (Rattus norvegicus)
pre-VLDL binds lipids to form VLDL (Sus scrofa)
Authored
Jassal, B  (2016-03-30)
Reviewed
D'Eustachio, P  (2016-04-05)
Created
Jassal, B  (2016-03-30)
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