Reactome | DERL3 [endoplasmic reticulum membrane]

DERL3 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-8866516

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Derlin-3, DERL3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96Q80 DERL3

Gene Names

DERL3, C22orf14, DER3, LLN2

Chain

chain:1-235

Reference Genes

BioGPS Gene:91319 DERL3

COSMIC (genes):DERL3 DERL3

CTD Gene:91319 DERL3

dbSNP Gene:91319 DERL3

ENSEMBL:ENSG00000099958 DERL3

ENSEMBL:ENSG00000274437 DERL3

HGNC:14236 DERL3

KEGG Gene (Homo sapiens):91319 DERL3

Monarch:91319 DERL3

NCBI Gene:91319 DERL3

OMIM:610305 DERL3

UCSC:Q96Q80 DERL3

Reference Transcript

Other Identifiers

0001940181

11728406_x_at

11728407_a_at

11728408_x_at

11733285_x_at

16933062

228897_at

229721_x_at

3954909

3954911

3954912

3954913

3954914

3954915

3954916

3954917

3954918

3954919

3954920

3954921

3954922

3954925

3954926

3954927

3954928

3954931

3954933

3954935

3954937

3954938

56599_i_at

56602_f_at

80262_at

8074944

91319

A_23_P6362

A_24_P239343

A_33_P3724155

A_33_P3724157

GE62539

GE872830

GO:0000839

GO:0003674

GO:0005047

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0006464

GO:0006810

GO:0006950

GO:0007165

GO:0008150

GO:0009056

GO:0009058

GO:0015031

GO:0016020

GO:0016021

GO:0018279

GO:0019899

GO:0030176

GO:0030433

GO:0030968

GO:0032991

GO:0043226

GO:0044877

GO:0051787

GO:1904153

GO:1990381

HMNXSV003023749

HMNXSV003034765

Hs.14587.0.S1_3p_x_at

Hs.14587.2.A1_3p_a_at

Hs.14587.2.A1_3p_x_at

ILMN_1651415

ILMN_1674899

ILMN_1731111

PH_hs_0031927

TC22000569.hg

Participates

as a candidate of

DERLs [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

DERL3 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

DERL3 [endoplasmic reticulum membrane] (Canis familiaris)

DERL3 [endoplasmic reticulum membrane] (Gallus gallus)

DERL3 [endoplasmic reticulum membrane] (Sus scrofa)

Der-2 [endoplasmic reticulum membrane] (Drosophila melanogaster)

derl3 [endoplasmic reticulum membrane] (Danio rerio)

Derl3 [endoplasmic reticulum membrane] (Mus musculus)

Derl3 [endoplasmic reticulum membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_940842.2, NP_001129223.1, XP_011528808.1, NP_001002862.1

OpenTargets

ENSG00000099958

HPA

ENSG00000099958-DERL3

GeneCards

Q96Q80

Ensembl

ENSG00000274437, ENSG00000099958, ENST00000620697, ENSP00000384744, ENST00000476077, ENSP00000419399, ENST00000406855, ENST00000628868, ENST00000318109, ENSP00000486587, ENSP00000483693, ENSP00000315303, ENSP00000485763, ENST00000631305

PRO

Q96Q80

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6UWB1 IL27RA	4	sIL27RA [extracellular region] (R-HSA-8950454) sIL27RA [cytoplasm] (R-HSA-8950653) p-Y611-IL27RA [plasma membrane] (R-HSA-8950330) IL27RA [plasma membrane] (R-HSA-448478)	0.556	3
UniProt:Q08426 EHHADH	2	EHHADH [cytosol] (R-HSA-9033147) EHHADH [peroxisomal matrix] (R-HSA-400155)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206) SDCBP [cytosol] (R-HSA-373639)	0.556	3
UniProt:Q05329 GAD2	2	PXLP-K396-GAD2 [plasma membrane] (R-HSA-936509) PXLP-K396-GAD2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888582)	0.556	3
UniProt:P22749 GNLY	2	GNLY [extracellular region] (R-HSA-6806691) GNLY [phagocytic vesicle lumen] (R-HSA-6807564)	0.556	3
UniProt:Q9UKG4 SLC13A4	1	SLC13A4 [plasma membrane] (R-HSA-433098)	0.556	3