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PPIL1 [nucleoplasm]
Stable Identifier
R-HSA-8867892
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Peptidyl-prolyl cis-trans isomerase-like 1, PPIL1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Cleavage at the 3'-Splice Site and Exon Ligation (Homo sapiens)
intron-containing complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
pre-EJC:Spliceosomal C:pre-mRNP:CBC [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Formation of Exon Junction Complex (Homo sapiens)
Spliceosomal active C complex with lariat containing, 5'-end cleaved pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
pre-EJC:Spliceosomal C:pre-mRNP:CBC [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Formation of an intermediate Spliceosomal C (Bact) complex (Homo sapiens)
Spliceosomal B Complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Spliceosomal Intermediate C (Bact) Complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B Complex (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Spliceosomal B Complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Formation of the active Spliceosomal C (B*) complex (Homo sapiens)
Spliceosomal Active C (B*) Complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Spliceosomal Intermediate C (Bact) Complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Lariat Formation and 5'-Splice Site Cleavage (Homo sapiens)
Spliceosomal Active C (B*) Complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
Spliceosomal active C complex with lariat containing, 5'-end cleaved pre-mRNP:CBC complex [nucleoplasm] (Homo sapiens)
PPIL [nucleoplasm] (Homo sapiens)
PPIL1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y3C6 PPIL1
Gene Names
PPIL1, CYPL1, CGI-124, UNQ2425/PRO4984
Chain
chain:1-166
Reference Genes
BioGPS Gene:51645 PPIL1
COSMIC (genes):PPIL1 PPIL1
CTD Gene:51645 PPIL1
dbSNP Gene:51645 PPIL1
ENSEMBL:ENSG00000137168 PPIL1
HGNC:9260 PPIL1
KEGG Gene (Homo sapiens):51645 PPIL1
Monarch:51645 PPIL1
NCBI Gene:51645 PPIL1
OMIM:601301 PPIL1
UCSC:Q9Y3C6 PPIL1
Reference Transcript
RefSeq:NM_016059.4 PPIL1
Other Identifiers
0001850193
11718035_at
11718036_at
11757669_s_at
17018685
222500_at
2952066
2952067
2952068
2952071
2952072
2952073
51169_at
51645
75054_at
8126058
A_23_P133995
GE58666
GO:0000398
GO:0000413
GO:0003674
GO:0003755
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005681
GO:0006397
GO:0006457
GO:0006464
GO:0008150
GO:0008380
GO:0016018
GO:0016853
GO:0032991
GO:0034641
GO:0043226
GO:0071007
GO:0071013
GO:0097718
ILMN_1768782
ILMN_2054392
TC06001679.hg
g12804374_3p_at
Participant Of
hasMember
PPIL [nucleoplasm]
Inferred To
cypE [nucleoplasm] (Dictyostelium discoideum)
PPIL1 [nucleoplasm] (Canis familiaris)
PPIL1 [nucleoplasm] (Gallus gallus)
PPIL1 [nucleoplasm] (Sus scrofa)
PPIL1 [nucleoplasm] (Xenopus tropicalis)
ppil1 [nucleoplasm] (Danio rerio)
Cypl [nucleoplasm] (Drosophila melanogaster)
cyn-12 [nucleoplasm] (Caenorhabditis elegans)
Ppil1 [nucleoplasm] (Mus musculus)
Ppil1 [nucleoplasm] (Rattus norvegicus)
Cross References
RefSeq
NP_057143.1
Target Pathogen
5b354852be737e166372ee94
OpenTargets
ENSG00000137168
IntEnz
5.2.1.8
HPA
ENSG00000137168-PPIL1
GeneCards
Q9Y3C6
Ensembl
ENSG00000137168
,
ENST00000373699
,
ENSP00000362803
PRO
Q9Y3C6
PDB
6FF4
,
5YZG
,
2K7N
,
5Z57
,
5XJC
,
1XWN
,
5MQF
,
6ID0
,
6FF7
,
2X7K
,
6ID1
,
6ICZ
,
6QDV
,
5Z56
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.897
15
UniProt:Q9CSN1 Snw1
1
Snw1 [nucleoplasm]
(R-MMU-2065315)
0.564
2
UniProt:Q9UMD9 COL17A1
48
GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173084)
GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173102)
3x4Hyp-GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173190)
3x4Hyp-3Hyp-GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173237)
3x4Hyp-GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173184)
3x4Hyp-3Hyp-GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173264)
COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2172232)
3x4Hyp-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2172934)
3x4Hyp-3Hyp-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2172989)
3x4Hyp-5Hyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173162)
3x4Hyp-3Hyp-5Hyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173230)
5Hyl-COL17A1(1-1497) [endoplasmic reticulum lumen]
(R-HSA-2173044)
3x4Hyp-GalHyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471866)
5Hyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471851)
3x4Hyp-3Hyp-COL17A1(?-1497) [extracellular region]
(R-HSA-2471867)
3x4Hyp-5Hyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471913)
3x4Hyp-3Hyp-5Hyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471897)
COL17A1(?-1497) [extracellular region]
(R-HSA-2471870)
GalHyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471903)
3x4Hyp-3Hyp-GlcGalHyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471916)
3x4Hyp-COL17A1(?-1497) [extracellular region]
(R-HSA-2471874)
3x4Hyp-3Hyp-GalHyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471859)
GlcGalHyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471862)
3x4Hyp-GlcGalHyl-COL17A1(?-1497) [extracellular region]
(R-HSA-2471861)
COL17A1(1-?) [plasma membrane]
(R-HSA-2471864)
3x4Hyp-GlcGalHyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471848)
3x4Hyp-GalHyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471912)
3x4Hyp-3Hyp-GalHyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471849)
5Hyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471871)
3x4Hyp-3Hyp-COL17A1(1-?) [plasma membrane]
(R-HSA-2471852)
COL17A1(1-1497) [plasma membrane]
(R-HSA-445994)
GlcGalHyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192833)
GalHyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192832)
3x4Hyp-GalHyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192834)
3x4Hyp-3Hyp-GlcGalHyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192837)
3x4Hyp-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192836)
3x4Hyp-3Hyp-5Hyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192839)
3x4Hyp-5Hyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192841)
3x4Hyp-GlcGalHyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192840)
3x4Hyp-3Hyp-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192843)
5Hyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192842)
3x4Hyp-3Hyp-GalHyl-COL17A1(1-1497) [plasma membrane]
(R-HSA-2192831)
3x4Hyp-3Hyp-GlcGalHyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471893)
GlcGalHyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471892)
GalHyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471863)
3x4Hyp-5Hyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471841)
3x4Hyp-COL17A1(1-?) [plasma membrane]
(R-HSA-2471872)
3x4Hyp-3Hyp-5Hyl-COL17A1(1-?) [plasma membrane]
(R-HSA-2471853)
0.556
3
UniProt:P50458 LHX2
1
LHX2 [nucleoplasm]
(R-HSA-9011100)
0.556
3
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