Reactome | PPIL1 [nucleoplasm]

PPIL1 [nucleoplasm]

Stable Identifier

R-HSA-8867892

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Peptidyl-prolyl cis-trans isomerase-like 1, PPIL1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y3C6 PPIL1

Gene Names

PPIL1, CYPL1, CGI-124, UNQ2425/PRO4984

Chain

chain:1-166

Reference Genes

BioGPS Gene:51645 PPIL1

COSMIC (genes):PPIL1 PPIL1

CTD Gene:51645 PPIL1

dbSNP Gene:51645 PPIL1

ENSEMBL:ENSG00000137168 PPIL1

HGNC:9260 PPIL1

KEGG Gene (Homo sapiens):51645 PPIL1

Monarch:51645 PPIL1

NCBI Gene:51645 PPIL1

OMIM:601301 PPIL1

UCSC:Q9Y3C6 PPIL1

Reference Transcript

RefSeq:NM_016059.4 PPIL1

Other Identifiers

0001850193

11718035_at

11718036_at

11757669_s_at

17018685

222500_at

2952066

2952067

2952068

2952071

2952072

2952073

51169_at

51645

75054_at

8126058

A_23_P133995

GE58666

GO:0000398

GO:0000413

GO:0003674

GO:0003755

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005681

GO:0006397

GO:0006457

GO:0006464

GO:0008150

GO:0008380

GO:0016018

GO:0016853

GO:0032991

GO:0034641

GO:0043226

GO:0071007

GO:0071013

GO:0097718

ILMN_1768782

ILMN_2054392

TC06001679.hg

g12804374_3p_at

Participant Of

hasMember

PPIL [nucleoplasm]

Inferred To

cypE [nucleoplasm] (Dictyostelium discoideum)

PPIL1 [nucleoplasm] (Canis familiaris)

PPIL1 [nucleoplasm] (Gallus gallus)

PPIL1 [nucleoplasm] (Sus scrofa)

PPIL1 [nucleoplasm] (Xenopus tropicalis)

ppil1 [nucleoplasm] (Danio rerio)

Cypl [nucleoplasm] (Drosophila melanogaster)

cyn-12 [nucleoplasm] (Caenorhabditis elegans)

Ppil1 [nucleoplasm] (Mus musculus)

Ppil1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_057143.1

Target Pathogen

5b354852be737e166372ee94

OpenTargets

ENSG00000137168

IntEnz

5.2.1.8

HPA

ENSG00000137168-PPIL1

GeneCards

Q9Y3C6

Ensembl

ENSG00000137168, ENST00000373699, ENSP00000362803

PRO

Q9Y3C6

PDB

6FF4, 5YZG, 2K7N, 5Z57, 5XJC, 1XWN, 5MQF, 6ID0, 6FF7, 2X7K, 6ID1, 6ICZ, 6QDV, 5Z56

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.897	15
UniProt:Q9CSN1 Snw1	1	Snw1 [nucleoplasm] (R-MMU-2065315)	0.564	2
UniProt:Q9UMD9 COL17A1	48	GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173084) GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173102) 3x4Hyp-GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173190) 3x4Hyp-3Hyp-GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173237) 3x4Hyp-GalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173184) 3x4Hyp-3Hyp-GlcGalHyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173264) COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2172232) 3x4Hyp-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2172934) 3x4Hyp-3Hyp-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2172989) 3x4Hyp-5Hyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173162) 3x4Hyp-3Hyp-5Hyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173230) 5Hyl-COL17A1(1-1497) [endoplasmic reticulum lumen] (R-HSA-2173044) 3x4Hyp-GalHyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471866) 5Hyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471851) 3x4Hyp-3Hyp-COL17A1(?-1497) [extracellular region] (R-HSA-2471867) 3x4Hyp-5Hyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471913) 3x4Hyp-3Hyp-5Hyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471897) COL17A1(?-1497) [extracellular region] (R-HSA-2471870) GalHyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471903) 3x4Hyp-3Hyp-GlcGalHyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471916) 3x4Hyp-COL17A1(?-1497) [extracellular region] (R-HSA-2471874) 3x4Hyp-3Hyp-GalHyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471859) GlcGalHyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471862) 3x4Hyp-GlcGalHyl-COL17A1(?-1497) [extracellular region] (R-HSA-2471861) COL17A1(1-?) [plasma membrane] (R-HSA-2471864) 3x4Hyp-GlcGalHyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471848) 3x4Hyp-GalHyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471912) 3x4Hyp-3Hyp-GalHyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471849) 5Hyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471871) 3x4Hyp-3Hyp-COL17A1(1-?) [plasma membrane] (R-HSA-2471852) COL17A1(1-1497) [plasma membrane] (R-HSA-445994) GlcGalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192833) GalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192832) 3x4Hyp-GalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192834) 3x4Hyp-3Hyp-GlcGalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192837) 3x4Hyp-COL17A1(1-1497) [plasma membrane] (R-HSA-2192836) 3x4Hyp-3Hyp-5Hyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192839) 3x4Hyp-5Hyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192841) 3x4Hyp-GlcGalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192840) 3x4Hyp-3Hyp-COL17A1(1-1497) [plasma membrane] (R-HSA-2192843) 5Hyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192842) 3x4Hyp-3Hyp-GalHyl-COL17A1(1-1497) [plasma membrane] (R-HSA-2192831) 3x4Hyp-3Hyp-GlcGalHyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471893) GlcGalHyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471892) GalHyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471863) 3x4Hyp-5Hyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471841) 3x4Hyp-COL17A1(1-?) [plasma membrane] (R-HSA-2471872) 3x4Hyp-3Hyp-5Hyl-COL17A1(1-?) [plasma membrane] (R-HSA-2471853)	0.556	3
UniProt:P50458 LHX2	1	LHX2 [nucleoplasm] (R-HSA-9011100)	0.556	3

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