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PRPF38A [nucleoplasm]
Stable Identifier
R-HSA-8867897
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Pre-mRNA-splicing factor 38A, PR38A_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P84103 SRSF3
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
PRPF38A [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
PRPF38A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8NAV1 PRPF38A
Gene Names
PRPF38A
Chain
chain:1-312
Reference Genes
BioGPS Gene:84950 PRPF38A
COSMIC (genes):PRPF38A PRPF38A
CTD Gene:84950 PRPF38A
dbSNP Gene:84950 PRPF38A
ENSEMBL:ENSG00000134748 PRPF38A
HGNC:25930 PRPF38A
KEGG:hsa:84950 PRPF38A
Monarch:84950 PRPF38A
NCBI Gene:84950 PRPF38A
UCSC:Q8NAV1 PRPF38A
Reference Transcript
RefSeq:NM_032864.3 PRPF38A
Other Identifiers
11743069_a_at
11743070_at
1553709_PM_a_at
1553709_a_at
16664731
223230_PM_at
223230_at
2336384
2336385
2336387
2336388
2336389
2336390
2336392
2336395
2336396
2336398
2336399
2336401
2336402
2336403
2336404
2336405
2336406
2336407
2336409
2336411
2336413
235612_PM_at
235612_at
3237076
3237083
45968_at
7901447
83593_at
84950
87910_s_at
A_14_P202139
A_24_P88493
A_24_P97001
GE83362
GO:0000398
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0006397
GO:0008380
GO:0016071
GO:0043226
GO:0071005
GO:0071011
HMNXSV003008195
Hs.34644.0.A1_3p_at
Hs.5301.0.S2_3p_at
Hs2.5301.2.S1_3p_s_at
ILMN_1656274
ILMN_1675626
PH_hs_0000542
TC01000641.hg
Participates
as an input of
Formation of the Spliceosomal B complex (Homo sapiens)
as an output of
Formation of the Spliceosomal Bact complex (Homo sapiens)
as a component of
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
Inferred To
prp38 [nucleoplasm]
(Schizosaccharomyces pombe)
PRPF38A [nucleoplasm]
(Bos taurus)
PRPF38A [nucleoplasm]
(Canis familiaris)
PRPF38A [nucleoplasm]
(Gallus gallus)
PRPF38A [nucleoplasm]
(Plasmodium falciparum)
PRPF38A [nucleoplasm]
(Sus scrofa)
Prpf38a [nucleoplasm]
(Mus musculus)
Prpf38a [nucleoplasm]
(Rattus norvegicus)
prp-38 [nucleoplasm]
(Caenorhabditis elegans)
prpf38a [nucleoplasm]
(Dictyostelium discoideum)
prpf38a [nucleoplasm]
(Xenopus tropicalis)
Prp38 [nucleoplasm]
(Drosophila melanogaster)
Cross References
RefSeq
NP_116253.2
OpenTargets
ENSG00000134748
ENSEMBL
ENST00000257181
,
ENSP00000257181
HPA
ENSG00000134748-PRPF38A
PRO
Q8NAV1
Pharos - Targets
Q8NAV1
GlyGen
Q8NAV1
PDB
7AAV
,
4RZ9
,
5F5S
,
7ABI
,
8Q7N
,
5O9Z
,
8QPE
,
7ABG
,
8QZS
,
7ABF
,
6AHD
,
8H6K
,
8QO9
,
4RZA
Interactors (20)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.855
7
UniProt:Q9H190 SDCB2
0.781
7
UniProt:Q96SB4 SRPK1
2
SRPK1 [nucleoplasm]
(R-HSA-9821984)
SRPK1 [cytosol]
(R-HSA-9729349)
0.693
3
UniProt:P55081 MFAP1
1
MFAP1 [nucleoplasm]
(R-HSA-2396419)
0.671
4
UniProt:P84103 SRSF3
1
SRSF3 [nucleoplasm]
(R-HSA-72035)
0.641
3
UniProt:Q6NYC1 JMJD6
1
JMJD6 [nucleoplasm]
(R-HSA-4754226)
0.632
5
UniProt:Q96CW1 AP2M1
6
AP2M1 [plasma membrane]
(R-HSA-167585)
AP2M1 [lysosomal membrane]
(R-HSA-196144)
AP2M1 [cytosol]
(R-HSA-182227)
AP2M1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130423)
AP2M1 [endolysosome membrane]
(R-HSA-6784828)
p-T156 AP2M1 [cytosol]
(R-HSA-8856805)
0.556
5
UniProt:Q92997 DVL3
4
pp-DVL3 [cytosol]
(R-HSA-3772400)
p-DVL3 [cytosol]
(R-HSA-201680)
DVL3 [cytosol]
(R-HSA-201678)
ub-DVL3 [cytosol]
(R-HSA-4652688)
0.556
3
UniProt:Q16629 SRSF7
1
SRSF7 [nucleoplasm]
(R-HSA-72029)
0.556
3
UniProt:P49760 CLK2
0.556
3
UniProt:O00560 SDCBP
3
SDCBP [cytosol]
(R-HSA-373639)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [extracellular region]
(R-HSA-6806206)
0.556
3
UniProt:P55735 SEC13
4
SEC13 [lysosomal membrane]
(R-HSA-9638246)
SEC13 [endoplasmic reticulum membrane]
(R-HSA-203994)
SEC13 [ER to Golgi transport vesicle membrane]
(R-HSA-204012)
SEC13 [cytosol]
(R-HSA-203981)
0.527
3
UniProt:Q13247 SRSF6
1
SRSF6 [nucleoplasm]
(R-HSA-72026)
0.508
2
UniProt:P62277 RPS13
2
RPS13 [cytosol]
(R-HSA-72331)
RPS13 [nucleoplasm]
(R-HSA-6791198)
0.508
2
UniProt:Q12888 TP53BP1
3
TP53BP1 [nucleoplasm]
(R-HSA-61175)
p-S25,S1778-TP53BP1 [nucleoplasm]
(R-HSA-5683418)
monoSUMO1-K-TP53BP1 [nucleoplasm]
(R-HSA-2997591)
0.508
2
UniProt:P23527 H2BC17
9
Ub-HIST1H2BO [nucleoplasm]
(R-HSA-6782549)
AcK-HIST1H2BO [nucleoplasm]
(R-HSA-4549268)
HIST1H2BO [extracellular region]
(R-HSA-977557)
AcK13-HIST1H2BO [nucleoplasm]
(R-HSA-4568712)
AcK21-HIST1H2BO [nucleoplasm]
(R-HSA-4568713)
AcK16-HIST1H2BO [nucleoplasm]
(R-HSA-4568681)
AcK6-HIST1H2BO [nucleoplasm]
(R-HSA-4568708)
Ub-121-HIST1H2BO [nucleoplasm]
(R-HSA-3364033)
HIST1H2BO [nucleoplasm]
(R-HSA-181910)
0.508
2
UniProt:Q13243 SRSF5
1
SRSF5 [nucleoplasm]
(R-HSA-72028)
0.508
2
UniProt:Q15329 E2F5
1
E2F5 [nucleoplasm]
(R-HSA-68669)
0.508
2
UniProt:Q9NVR5 KTU
0.508
2
UniProt:Q9Y6A4 CFA20
0.508
2
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