Reactome | p-T90-PRDX1 [cytosol]

p-T90-PRDX1 [cytosol]

Stable Identifier

R-HSA-8868564

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q06830 PRDX1

Gene Names

PRDX1, PAGA, PAGB, TDPX2

Chain

initiator methionine:1, chain:2-199

Reference Genes

BioGPS Gene:5052 PRDX1

COSMIC (genes):PRDX1 PRDX1

CTD Gene:5052 PRDX1

dbSNP Gene:5052 PRDX1

ENSEMBL:ENSG00000117450 PRDX1

HGNC:9352 PRDX1

KEGG Gene (Homo sapiens):5052 PRDX1

Monarch:5052 PRDX1

NCBI Gene:5052 PRDX1

OMIM:176763 PRDX1

UCSC:Q06830 PRDX1

Reference Transcript

Other Identifiers

0004070072

00480+1.11.1.15

11742924_a_at

16686472

208680_at

2410243

2410244

2410245

2410246

2410247

2410248

2410249

2410250

2410252

2410253

2RII

3198940

3HY2

41213_at

4682

4XCS

5052

7730

7915733

A0A0A0MRQ5

A0A0A0MSI0

A0A384NPQ2

A_23_P11995

A_33_P3377199

AAA50464

AAH07063

AAH21683

AAV38545

AB451262

AB451388

ABB84465

ADO22248

AL451136

BAG70076

BAG70202

BC007063

BC021683

BT019740

CAA48137

CAB004682

CAG28580

CCDS522

CH471059

CR407652

DQ297142

EAX06975

EAX06976

EAX06978

EAX06979

EAX06980

EAX06981

EAX06982

ENSG00000117450

ENSP00000262746

ENSP00000361152

ENST00000262746

ENST00000262746.5

ENST00000319248

ENST00000319248.12

EntrezGene:5052

EntrezGene:PRDX1

g440305_3p_s_at

GE62148

GO:0000302

GO:0001501

GO:0001895

GO:0002376

GO:0003674

GO:0003723

GO:0004601

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005623

GO:0005634

GO:0005737

GO:0005829

GO:0006464

GO:0006950

GO:0006979

GO:0007165

GO:0008150

GO:0008283

GO:0008379

GO:0009056

GO:0016209

GO:0016491

GO:0019430

GO:0030101

GO:0031410

GO:0032872

GO:0034101

GO:0034599

GO:0042267

GO:0042470

GO:0042592

GO:0042744

GO:0042802

GO:0043226

GO:0045296

GO:0045321

GO:0045454

GO:0048856

GO:0051186

GO:0051920

GO:0055114

GO:0070062

GO:1901222

GQ891386

HGNC:9352

HPA007730

ILMN_1710159

ILMN_2366388

ILMN_2366391

IPR000866

IPR013766

IPR019479

IPR024706

IPR036249

L19184

MIM:176763

MIM:277400

NM_001202431

NM_002574

NM_181696

NM_181697

NP_001189360

NP_002565

NP_859047

NP_859048

PF00578

PF10417

PH_hs_0029347

PRDX1

PRDX1-201

PRDX1-202

TC01002611.hg

UPI000002FC88

X67951

X67951_at

Participant Of

output

CDK5:p25 phosphorylates PRDX1

Other forms of this molecule

HOOS-C52-PRDX1 [cytosol]

PRDX1 [cytosol]

Modified Residues

Name

O-phospho-L-threonine at 90

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_002565.1, NP_859047.1, NP_001189360.1, NP_859048.1

OpenTargets

ENSG00000117450

GeneCards

Q06830

PRO

Q06830

PDB

2RII, 3HY2, 4XCS

HMDB Protein

HMDBP02990

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13043 STK4	4	STK4(1-487) [cytosol] (R-HSA-201627) p-T183-STK4(1-487) [cytosol] (R-HSA-2028258) p-T183-STK4(1-326) [cytosol] (R-HSA-2028682) STK4(327-487) [cytosol] (R-HSA-2028668)	0.66	11
UniProt:P60484 PTEN	122	PTEN [nucleoplasm] (R-HSA-5690148) K48polyUb-PTEN [cytosol] (R-HSA-8874327) PolyUb-PTEN [nucleoplasm] (R-HSA-6782515) PTEN H93R [cytosol] (R-HSA-2318524) PTEN C124R [cytosol] (R-HSA-2317439) PTEN H93Y [cytosol] (R-HSA-2318520) PTEN R130G [cytosol] (R-HSA-2317339) PTEN H93D [cytosol] (R-HSA-2318550) PTEN R130L [cytosol] (R-HSA-2317430) PTEN H93A [cytosol] (R-HSA-2318544) PTEN G129E [cytosol] (R-HSA-2318509) PTEN S170N [cytosol] (R-HSA-2318408) PTEN R173P [cytosol] (R-HSA-2317480) PTEN R130Q [cytosol] (R-HSA-2317416) PTEN H93Q [cytosol] (R-HSA-2318565) PTEN G129R [cytosol] (R-HSA-2318501) PTEN H123Y [cytosol] (R-HSA-2318469) PTEN S170R [cytosol] (R-HSA-2318437) PTEN R173C [cytosol] (R-HSA-2317478) PTEN R173H [cytosol] (R-HSA-2317473) PTEN C124S [cytosol] (R-HSA-2317379) PTEN C124Y [cytosol] (R-HSA-2317464) PTEN R130P [cytosol] (R-HSA-2317432) PTEN C124F [cytosol] (R-HSA-2317461) PTEN G129V [cytosol] (R-HSA-2318503) PTEN S170I [cytosol] (R-HSA-2318455) PTEN S170G [cytosol] (R-HSA-2318465) PTEN E99* [cytosol] (R-HSA-9659052) PTEN G165* [cytosol] (R-HSA-9659117) PTEN E157* [cytosol] (R-HSA-9658926) PTEN E150* [cytosol] (R-HSA-9658920) PTEN E43* [cytosol] (R-HSA-9659049) PTEN Q17* [cytosol] (R-HSA-9659305) PTEN E91* [cytosol] (R-HSA-9659050) PTEN S59* [cytosol] (R-HSA-9659360) PTEN E114* [cytosol] (R-HSA-9658915) PTEN L139* [cytosol] (R-HSA-9659196) PTEN Y176* [cytosol] (R-HSA-9659389) PTEN Y177* [cytosol] (R-HSA-9659390) PTEN Q149* [cytosol] (R-HSA-9659320) PTEN L146* [cytosol] (R-HSA-9659193) PTEN G20* [cytosol] (R-HSA-9659129) PTEN G127* [cytosol] (R-HSA-9659130) PTEN Y46* [cytosol] (R-HSA-9659387) PTEN L182* [cytosol] (R-HSA-9659189) PTEN Q97* [cytosol] (R-HSA-9659318) PTEN Q171* [cytosol] (R-HSA-9659312) PTEN G129* [cytosol] (R-HSA-9659120) PTEN E18* [cytosol] (R-HSA-9658931) PTEN Y180* [cytosol] (R-HSA-9659404) PTEN K163* [cytosol] (R-HSA-9659148) PTEN Y27* [cytosol] (R-HSA-9659405) PTEN Y65* [cytosol] (R-HSA-9659406) PTEN Y68* [cytosol] (R-HSA-9659400) PTEN K128* [cytosol] (R-HSA-9659145) PTEN Y138* [cytosol] (R-HSA-9659402) PTEN K125* [cytosol] (R-HSA-9659147) PTEN Y88* [cytosol] (R-HSA-9659399) PTEN Q110* [cytosol] (R-HSA-9659328) PTEN L23* [cytosol] (R-HSA-9659201) PTEN E7* [cytosol] (R-HSA-9659036) PTEN C105* [cytosol] (R-HSA-9658911) PTEN E73* [cytosol] (R-HSA-9659039) PTEN K62* [cytosol] (R-HSA-9659160) PTEN E40* [cytosol] (R-HSA-9659032) PTEN Y178* [cytosol] (R-HSA-9659417) PTEN R130* [cytosol] (R-HSA-2318571) PTEN W111* [cytosol] (R-HSA-9659414) PTEN R11* [cytosol] (R-HSA-9659350) PTEN K13* [cytosol] (R-HSA-9659152) PTEN Y174* [cytosol] (R-HSA-9659409) PTEN K147* [cytosol] (R-HSA-9659153) PTEN R84* [cytosol] (R-HSA-9659347) PTEN G293* [cytosol] (R-HSA-9659113) PTEN S287* [cytosol] (R-HSA-9659371) PTEN Q214* [cytosol] (R-HSA-9659307) PTEN S229* [cytosol] (R-HSA-9659366) PTEN Q219* [cytosol] (R-HSA-9659302) PTEN Q261* [cytosol] (R-HSA-9659303) PTEN E299* [cytosol] (R-HSA-9659040) PTEN Y336* [cytosol] (R-HSA-9659388) PTEN Q245* [cytosol] (R-HSA-9659326) PTEN Y225* [cytosol] (R-HSA-9659391) PTEN Y240* [cytosol] (R-HSA-9659385) PTEN C218* [cytosol] (R-HSA-9659065) PTEN C250* [cytosol] (R-HSA-9659066) PTEN L247* [cytosol] (R-HSA-9659195) PTEN G209* [cytosol] (R-HSA-9659124) PTEN C211* [cytosol] (R-HSA-9659062) PTEN G230* [cytosol] (R-HSA-9659121) PTEN Q298* [cytosol] (R-HSA-9659314) PTEN L320* [cytosol] (R-HSA-9659187) PTEN E242* [cytosol] (R-HSA-9659084) PTEN K332* [cytosol] (R-HSA-9659151) PTEN E284* [cytosol] (R-HSA-9659087) PTEN E291* [cytosol] (R-HSA-9659081) PTEN K330* [cytosol] (R-HSA-9659146) PTEN E314* [cytosol] (R-HSA-9659078) PTEN Y346* [cytosol] (R-HSA-9659392) PTEN C296* [cytosol] (R-HSA-9659072) PTEN W274* [cytosol] (R-HSA-9659393) PTEN R233* [cytosol] (R-HSA-2318573) PTEN R335* [cytosol] (R-HSA-2318568) PTEN E256* [cytosol] (R-HSA-9659098) PTEN R189* [cytosol] (R-HSA-9659354) PTEN E307* [cytosol] (R-HSA-9659099) PTEN K263* [cytosol] (R-HSA-9659156) PTEN E235* [cytosol] (R-HSA-9659029) PTEN E288* [cytosol] (R-HSA-9659094) PTEN K221* [cytosol] (R-HSA-9659158) PTEN K344* [cytosol] (R-HSA-9659159) p-Y336-PTEN [cytosol] (R-HSA-8847980) PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (R-HSA-8948841) RibC-E40,E150,D326-PTEN [cytosol] (R-HSA-8948798) p-3S,2T-PTEN [cytosol] (R-HSA-8850936) PTEN [cytosol] (R-HSA-199420) PTEN [nucleoplasm] (R-HSA-6807273) MonoUb-K13,K289-PTEN [nucleoplasm] (R-HSA-6807264) MonoUb-K13,K289-PTEN [cytosol] (R-HSA-6807247) K48polyUb-K289-PTEN [cytosol] (R-HSA-8948777) PolyUb-PTEN [cytosol] (R-HSA-6807280) K27polyUb-PTEN [cytosol] (R-HSA-8851009)	0.632	7
UniProt:Q9BYN0 SRXN1			0.618	3
UniProt:P13693 TCTP			0.567	4
UniProt:P10275 AR	4	SUMO1-K386,520-AR [nucleoplasm] (R-HSA-4090320) PolyUb-AR [nucleoplasm] (R-HSA-6782984) AR [cytosol] (R-HSA-5618082) AR [nucleoplasm] (R-HSA-446174)	0.544	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P54274 TERF1	1	TERF1 [nucleoplasm] (R-HSA-164618)	0.508	2
UniProt:P04156 PRNP	2	PRNP [plasma membrane] (R-HSA-375060) PRNP [cytosol] (R-HSA-9617597)	0.499	4
UniProt:Q00005 2ABB			0.462	2