Reactome | GNL3 [nucleoplasm]

GNL3 [nucleoplasm]

Stable Identifier

R-HSA-8869324

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Guanine nucleotide-binding protein-like 3, GNL3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BVP2 GNL3

Gene Names

GNL3, E2IG3, NS

Chain

chain:1-549

Reference Genes

BioGPS Gene:26354 GNL3

COSMIC (genes):GNL3 GNL3

CTD Gene:26354 GNL3

dbSNP Gene:26354 GNL3

ENSEMBL:ENSG00000163938 GNL3

HGNC:29931 GNL3

KEGG:hsa:26354 GNL3

Monarch:26354 GNL3

NCBI Gene:26354 GNL3

OMIM:608011 GNL3

UCSC:Q9BVP2 GNL3

Reference Transcript

Other Identifiers

11717310_a_at

11749333_a_at

16941661

16941687

17119348

217850_PM_at

217850_at

2624075

2624076

2624077

2624078

2624079

2624081

2624082

2624083

2624084

2624085

2624086

2624087

2624088

2624089

2624091

2624092

2624093

2624095

2624096

2624097

2624098

2624099

2624100

2624101

2624102

2624103

2624104

2624105

2624106

2624107

2624108

2624109

26354

2794954

45778_at

71669_at

8080419

85559_at

A_14_P112971

A_14_P119974

A_14_P124901

A_21_P0000375

A_21_P0000462

A_23_P41025

A_32_P8120

GE63028

GE81919

GE88847

GO:0003723

GO:0005515

GO:0005525

GO:0005615

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0006355

GO:0016020

GO:0016604

GO:0017145

GO:0019827

GO:0030496

GO:0032206

GO:0033235

GO:0042127

GO:0043226

GO:0048027

GO:1902895

GO:1904816

HMNXSV003019673

HMNXSV003054322

HMNXSV003055028

ILMN_1790659

ILMN_1806106

ILMN_2324056

PH_hs_0029728

RNA147247|p0351_imsncRNA769

RNA33614|snoRNA_scaRNA_210_84

RNA33678|snoRNA_scaRNA_274_76

TC03000339.hg

TC03000340.hg

g7657047_3p_at

Participates

as a component of

GNL3:EBNA1BP2:DDX21:PES1 [nucleoplasm] (Homo sapiens)

Inferred To

GNL3 [nucleoplasm] (Bos taurus)

GNL3 [nucleoplasm] (Caenorhabditis elegans)

GNL3 [nucleoplasm] (Canis familiaris)

GNL3 [nucleoplasm] (Dictyostelium discoideum)

GNL3 [nucleoplasm] (Drosophila melanogaster)

GNL3 [nucleoplasm] (Mus musculus)

GNL3 [nucleoplasm] (Rattus norvegicus)

GNL3 [nucleoplasm] (Saccharomyces cerevisiae)

GNL3 [nucleoplasm] (Schizosaccharomyces pombe)

GNL3 [nucleoplasm] (Sus scrofa)

GNL3 [nucleoplasm] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000163938

ENSEMBL

ENST00000418458, ENSP00000395772, ENSP00000378278, ENST00000394799, ENSG00000163938

HPA

ENSG00000163938-GNL3

GeneCards

GNL3

PRO

Q9BVP2

Pharos - Targets

Q9BVP2

GlyGen

Q9BVP2

HMDB Protein

HMDBP08432

PDB

8FKZ, 8FKY, 8FKR, 8FKT, 8IR1, 8FKV, 8FKP, 8FKX, 8INK, 8IR3, 8FKU, 8FKW, 8IPX, 8IPD, 8FL0, 8IPY, 8FL3, 8FL4, 8FL2

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UKV8 AGO2	2	AGO2 [cytosol] (R-HSA-209723) AGO2 [nucleoplasm] (R-HSA-5578701)	0.641	3
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.597	4
UniProt:O14746 TERT	1	TERT [nucleoplasm] (R-HSA-163076)	0.537	3
UniProt:P40763 STAT3	12	p-Y705-STAT3 [nucleoplasm] (R-HSA-1112554) p-Y705-STAT3 [cytosol] (R-HSA-914048) STAT3 [cytosol] (R-HSA-539044) p-Y705-STAT3 [cytosol] (R-HSA-8983130) p-Y705-STAT3 [nucleoplasm] (R-HSA-9027589) p-S727-STAT3 [cytosol] (R-HSA-198705) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701429) AcK685- p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701435) p-STAT3 [cytosol] (R-HSA-8982823) p-STAT3 [nucleoplasm] (R-HSA-8983188) Unfolded STAT3 [cytosol] (R-HSA-6813811)	0.508	2
UniProt:O00410 IPO5	1	IPO5 [nucleoplasm] (R-HSA-192675)	0.483	3
UniProt:Q12906 ILF3	3	ILF3 [nucleoplasm] (R-HSA-9760401) ILF3 [cytosol] (R-HSA-450564) p-T188,T315-ILF3 [cytosol] (R-HSA-9836381)	0.483	2
UniProt:Q13616 CUL1	3	CUL1 [cytosol] (R-HSA-174230) CUL1 [nucleoplasm] (R-HSA-187551) G76-NEDD8-K720-CUL1 [cytosol] (R-HSA-8952519)	0.483	2
UniProt:Q9Y5B9 SUPT16H	1	SUPT16H [nucleoplasm] (R-HSA-112415)	0.483	2

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