Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
EBNA1BP2 [nucleoplasm]
Stable Identifier
R-HSA-8869325
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Probable rRNA-processing protein EBP2, EBP2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Homo sapiens)
GNL3:EBNA1BP2:DDX21:PES1 [nucleoplasm] (Homo sapiens)
EBNA1BP2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99848 EBNA1BP2
Gene Names
EBNA1BP2, EBP2
Chain
chain:1-306
Reference Genes
BioGPS Gene:10969 EBNA1BP2
COSMIC (genes):EBNA1BP2 EBNA1BP2
CTD Gene:10969 EBNA1BP2
dbSNP Gene:10969 EBNA1BP2
ENSEMBL:ENSG00000117395 EBNA1BP2
HGNC:15531 EBNA1BP2
Monarch:10969 EBNA1BP2
NCBI Gene:10969 EBNA1BP2
OMIM:614443 EBNA1BP2
UCSC:Q99848 EBNA1BP2
Reference Transcript
RefSeq:NM_001159936.1 EBNA1BP2
RefSeq:NM_006824.2 EBNA1BP2
Other Identifiers
10969
11742945_a_at
11748565_a_at
11756448_x_at
11760295_at
16686088
201323_PM_at
201323_at
2409221
2409222
2409223
2409226
2409228
2409230
2409231
2409232
2409233
2409234
2409235
2409236
2409237
2409238
2409239
2409240
2409241
2409242
2409243
2409244
2409246
2409247
2409252
2409253
2409254
2409259
2409262
2409263
36135_at
7915485
A_23_P103631
A_32_P226468
GE59511
GE885736
GO:0003723
GO:0005515
GO:0005634
GO:0005694
GO:0005730
GO:0006364
GO:0030687
GO:0034399
GO:0042254
GO:0042273
GO:0043226
HMNXSV003004513
HMNXSV003020508
Hs2Affx.1.382.S1_3p_s_at
ILMN_1768127
PH_hs_0016724
U86602_at
g5803110_3p_at
Participates
as a component of
GNL3:EBNA1BP2:DDX21:PES1 [nucleoplasm] (Homo sapiens)
Inferred To
EBP2 [nucleoplasm]
(Saccharomyces cerevisiae)
Ebna1bp2 [nucleoplasm]
(Mus musculus)
ebp2 [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of EBNA1BP2 [nucleoplasm]
(Rattus norvegicus)
ebna1bp2 [nucleoplasm]
(Xenopus tropicalis)
EBNA1BP2 [nucleoplasm]
(Bos taurus)
EBNA1BP2 [nucleoplasm]
(Caenorhabditis elegans)
EBNA1BP2 [nucleoplasm]
(Canis familiaris)
EBNA1BP2 [nucleoplasm]
(Dictyostelium discoideum)
EBNA1BP2 [nucleoplasm]
(Drosophila melanogaster)
EBNA1BP2 [nucleoplasm]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000236051
,
ENST00000236051
OpenTargets
ENSG00000117395
HPA
ENSG00000117395-EBNA1BP2
PRO
Q99848
Pharos - Targets
Q99848
GlyGen
Q99848
PDB
8FKW
,
8FKU
,
8FKS
,
8FKX
,
8FKV
,
8FKQ
,
8FKR
,
8FKT
,
8FKY
,
8FKP
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62633 CNBP
2
CNBP [cytosol]
(R-HSA-9759645)
MeR25,27-CNBP [cytosol]
(R-HSA-9759641)
0.564
2
UniProt:P62917 RPL8
3
RPL8 [cytosol]
(R-HSA-72490)
RPL8 [nucleoplasm]
(R-HSA-9630985)
3OHH216-RPL8 [nucleoplasm]
(R-HSA-9630976)
0.527
2
UniProt:O43159 RRP8
1
RRP8 [nucleoplasm]
(R-HSA-427524)
0.527
3
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
UniProt:P19525 EIF2AK2
5
EIF2AK2 [cytosol]
(R-HSA-168699)
p-EIF2AK2 [nucleoplasm]
(R-HSA-9836332)
p-EIF2AK2 [cytosol]
(R-HSA-9833834)
ISG15-EIF2AK2 [cytosol]
(R-HSA-9833968)
SUMO-EIF2AK2 [cytosol]
(R-HSA-9834829)
0.527
2
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.527
2
UniProt:P06748 NPM1
11
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [granular component]
(R-HSA-9017702)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.527
3
UniProt:P46776 RPL27A
3
RPL27A [cytosol]
(R-HSA-72442)
RPL27A [nucleoplasm]
(R-HSA-9630984)
3OHH39-RPL27A [nucleoplasm]
(R-HSA-9630970)
0.527
2
UniProt:P46781 RPS9
2
RPS9 [cytosol]
(R-HSA-72387)
RPS9 [nucleoplasm]
(R-HSA-6790663)
0.527
2
UniProt:P62241 RPS8
2
RPS8 [cytosol]
(R-HSA-72385)
RPS8 [nucleoplasm]
(R-HSA-6791203)
0.527
2
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.483
2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
