Reactome: A Curated Pathway Database

TFPA2A homodimer and NPM1 bind the NOP2 gene promoter

Stable Identifier
R-HSA-8869543
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

In response to retinoic acid treatment, TFAP2A (AP-2 alpha) homodimers in complex with NPM1 (nucleophosmin) are recruited to the AP-2 alpha response element in the promoter of the nucleolar protein NOP2 (p120) (Liu et al. 2007).

Literature References
Participants
Participant Of