SLC36A4 transports L-Trp from extracellular region to cytosol

Stable Identifier
R-HSA-8870352
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Plasma membrane-associated SLC36A4 (solute carrier family 36 member 4, also known as PAT4 - Proton-coupled amino acid transporter 4) mediates the uptake of extracellular L-Trp (L-tryptophan) (Pillai & Meredith 2011).
Literature References
PubMed ID Title Journal Year
21097500 SLC36A4 (hPAT4) is a high affinity amino acid transporter when expressed in Xenopus laevis oocytes

Pillai, SM, Meredith, D

J. Biol. Chem. 2011
Participants
Participates
Event Information
Catalyst Activity

L-tryptophan transmembrane transporter activity of SLC36A4 [plasma membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
Cite Us!