BCL2L11 (BIM) gene expression

Stable Identifier
R-HSA-8870686
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, mitochondrial outer membrane
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BCL2L11 (BIM) gene expression
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Transcription of the pro-apoptotic BCL2L11 (BIM) gene is stimulated by FOXO3 downstream of CDK5-mediated FOXO3 phosphorylation (Shi et al. 2016).

Literature References
PubMed ID Title Journal Year
26962010 Cdk5-FOXO3a axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models

Shi, C, Viccaro, K, Lee, HG, Shah, K

J. Cell. Sci. 2016
Participants
Input
Output
Participant Of
hasEvent
This event is regulated
Positively by
Disease
Name Identifier Synonyms
Alzheimer's disease 10652 AD, Alzheimers dementia, Alzheimer disease
Authored
Shah, K  (2016-02-23)
Created
Orlic-Milacic, M  (2016-05-11)